Acute trauma stimulates local repair but can also affect structures distant from the injury, for instance through the activity of circulating factors. To study the responses of remote tissues to injury and regeneration, we generated genome-wide profiles from zebrafish brains following experimental cardiac damage. Our findings indicate regulatory mechanisms that distinguish short- and long-range gene expression responses to injury.
Support or Funding Information
National Institutes of Health American Heart Association Fondation Leducq
National Institutes of Health American Heart Association Fondation Leducq
