(961.11) Creatine Nitrate and Caffeine Alone and Co-ingested on Cognition, Readiness to Perform, and Sleep Quality

Poster Board Number: E637

Andrew Newton (Jacksonville State University), Majid Koozehchian (Jacksonville State University), Gina Mabrey (Jacksonville State University), Scott Forbes (Brandon University), Monoem Haddad (Qatar University), Alireza Naderi (Islamic Azad University, Boroujerd Branch)

Background: Caffeine and creatine nitrate are two purported supplements that may alter cognitive function. The primary purpose was to examine the impacts of each supplement ingested individually and co-ingested on cognitive performance. A secondary purpose was to explore the effects of caffeine and creatine nitrate alone and co-ingested on subjective feelings of readiness and sleep quality.

Methods: In a double-blind, randomized, placebo-controlled cross over study, 12 resistance-trained participants (22±1 y; 180.0±9.5 cm; 85.9±15.1 kg) completed 4 conditions in random order: creatine nitrate (CN: 5 g/day + 0.675 g/day of maltodextrin), caffeine (CAF: 400 mg/day + 5 g/day of maltodextrin), CN+CAF (5 g/day of creatine nitrate + 400 mg/day of caffeine), and placebo (PL: 5.4 g/day of maltodextrin). Supplements were ingested for 7 days with a 7-day washout period between conditions. Before and after supplementation, participants completed a Stroop color-word test, in addition to a readiness to perform a visual analog scale and a sleep quality questionnaire (sleep latency and duration). The readiness to perform the questionnaire assessed sleep, vigor, optimism, energy, appetite, and soreness. Data were analyzed using a two-way (within-within) analysis of variance (p≤0.05) with a Tukey’s post hoc when appropriate.

Results: There was a significant interaction for the Stroop color-word interference (p=0.049), with the post hoc revealing that CN+CAF was superior to CN alone (CN+CAF: 65.9 ± 17.3; CN: 56.8 ± 10.8, p=0.007); however, no other conditions were significantly different. There was no interaction or main effects for the readiness to perform questionnaire or sleep quality (pgt;0.05).

Conclusion: CAF+CN appears to be superior for cognitive performance compared to CN alone. Overall, neither supplement ingested individually or together altered subjective readiness to perform or sleep quality.