It has got a lot of attention that a substitute based on calcium phosphate (CaP), an essential component of bone, Among bio-engineering materials for the development of scaffolds for bone tissue engineering. The methods to obtain CaP-based ceramics are two ways; chemical synthesis such as hydroxyapatite (HAP) and biological apatite obtained from tooth or bone. The latter are biocompatible, easy to be prepare, owing to be similar with human bones. WPU (waterborn polyurethane), used as a scaffold for bone tissue engineering, is synthesized as polyols and isocyanates, petrochemical . it related with environmental problems. In this study, livestock waste(premolars and molars) were used as bioapatite, and followed by incorporated a CMCS(carboxymethyl chitosan)/WPU support using WPU replaced with a biomass castor oil-based polyol. And compared with the HAP-based CMCS/WPU scaffold, the mechanical properties were measured. after seeding osteoblasts, biocompatibility testing was performed.
Support or Funding Information
This research was supported by Basic Science Research Program through NRF of South Korea funded by Ministry of Education grant numbers: 2020R1A6A3A01100150/ 2019R1I1A3A01063627
