(715.15) A Preliminary Report on the Variation of Respiratory Blood Pressure during Sleep in Patients with Hypertension
Monday, April 4, 2022
10:15 AM – 12:15 PM
Location: Exhibit/Poster Hall A-B - Pennsylvania Convention Center
Poster Board Number: E92
Jinan Wang (Fuwai hospital,The affiliated rehabilitation hospital of Chongqing medical university), Xingguo Sun (Fuwai hospital), Wenqi Tai (Fuwai hospital), Qingqing Zhou (Fuwai hospital,The affiliated rehabilitation hospital of Chongqing medical university), Yanfang Zhang (Fuwai hospital,The affiliated rehabilitation hospital of Chongqing medical university)
Presenting Author Fuwai Hospital, The Affiliated Rehabilitation Hospital of Chongqing Medical University
Objective: Explore whether the blood pressure of hypertensive patients changes periodically with respiration.
Methods: This study analyzed 8 patients with hypertension without sleep apnea who performed cardiopulmonary exercise testing (CPET), polysomnography (PSG), continuous fingertip pulse wave and electrocardiogram (ECG), and compared with 8 normal subjects evaluated in the same period. Calculate the number of respiratory cycles (Bn), average respiratory cycle time (Bn-T) and other respiratory parameters as well as systolic blood pressure (SBP), diastolic blood pressure (DBP), blood pressure variation cycles (BPV-n), average blood pressure variation cycle time ( BPV-T) and other blood pressure variability parameters. Continuous variables within and between groups were compared by independent-sample t test, and data calculated by different methods in the same group were compared by paired-sample t test.
Results: The core parameters of CPET such as peak oxygen uptake (72.82±10.07%Pred) and anaerobic threshold (59.69±6.66%Pred) of hypertensive patients without sleep apnea were significantly lower than those of normal subjects (Plt;0.05). The fingertip pulse wave calculation of SBPV-n (7000.25±1404.78) and DBPV-n (6949.25±1407.98) in hypertensive patients were basically the same, similar to the results of normal subjects, and there was no statistically significant difference between the two groups (Pgt;0.05); SBPV-T, DBPV-T, SBPV rate and DBPV rate (4.34±0.72 s, 4.37±0.70 s, 14.22±2.39 bpm, 14.10±2.34 bpm) were not statistically different from normal subjects (Pgt;0.05); Bn/SBPV-n (1.00±0.03) and Bn/DBPV-n (1.01±0.02) are basically the same as normal subjects (Pgt;0.05), and both are close to 1.SBPV-n (2464.75±1318.38) and DBPV-n (936.00±132.18) calculated based on pulse transit time during sleep were significantly lower than the fingertip pulse wave calculation parameter (Plt;0.01). The systolic blood pressure variation amplitude (2.96±0.83 mmHg) and diastolic blood pressure variation amplitude (2.57±0.38 mmHg) were greater than those of normal subjects, but the difference was not statistically significant.
Conclusion: The variability of blood pressure during sleep in hypertensive patients without sleep apnea is similar to variability of respiration, and the change trend is consistent with normal subjects, both blood pressure variability is caused by respiration.
