Session 12: Desmoid Fibromatosis

Chair(s)

• 

  Torsten Nielsen, MD, PhD

  Professor of Pathology
  Department of Pathology, VGH
  Vancouver, British Columbia, Canada

Moderator(s)

• 

  Chiara Colombo, N/A, MD

  Surgical Oncologist
  Fondazione IRCCS Istituto Nazionale dei Tumori
  Milan, Lombardia, Italy
• 

  Bernd Kasper, MD, PhD

  Associate Professor
  University of Heidelberg, Mannheim University Medical Center, Mannheim Cancer Center, Sarcoma Unit,
  Mannheim, Baden-Wurttemberg, Germany

Presentations:

• 1:00 PM – 1:08 PM

  ACTIVE SURVEILLANCE IN PATIENTS WITH DESMOID-TYPE FIBROMATOSIS: A COMBINED ANALYSIS OF TWO PROSPECTIVE OBSERVATIONAL STUDIES
  

  Author: Chiara Colombo, N/A, MD – Fondazione IRCCS Istituto Nazionale dei Tumori

  Presenter: Anne-Rose W. Schut, MD (she/her/hers) – Erasmus Medical Center Rotterdam

  Co-Author: Francesco Barretta, PhD (he/him/his) – Fondazione IRCCS Istituto Nazionale dei Tumori

  Co-Author: Dirk J. Grünhagen, N/A, MD, PhD – Erasmus Medical Center

  Co-Author: Marco Fiore, MD, FACS, FEBS – Fondazione IRCCS Istituto Nazionale dei Tumori

  Co-Author: Milea J.M. Timbergen, MD, PhD – Erasmus Medical Center Rotterdam

  Co-Author: Elena Palassini, N/A, MD – Fondazione IRCCS Istituto Nazionale dei Tumori

  Co-Author: Danique L.M. van Broekhoven, MD, PhD – Erasmus Medical Center Rotterdam

  Co-Author: Giovanni Grignani, MD – Department of Medical Oncology-Sarcoma Unit, Candiolo Cancer Institute FPO-IRCCS, Candiolo (TO), Italy

  Co-Author: Thijs van Dalen, MD, PhD – University Medical Center Utrecht

  Co-Author: Francesco Tolomeo, MD – Candiolo Cancer Institute FPO-IRCCS, Candiolo (TO), Italy

  Co-Author: Winan J. Van Houdt, MSc, MD, PhD – The Netherlands Cancer Institute

  Co-Author: Paola Collini, MD – Fondazione IRCCS Istituto Nazionale dei Tumori

  Co-Author: Han Bonenkamp, MSc, MD, PhD (he/him/his) – Radboud University Medical Center

  Co-Author: Alessandra Merlini, MD – Department of Oncology, University of Turin

  Co-Author: Stefan Sleijfer, MD, PhD – Erasmus Medical Center Rotterdam

  Co-Author: Frits van Coevorden, MD, PhD (he/him/his) – The Netherlands Cancer Institute

  Co-Author: Federica Perrone, MD – Fondazione IRCCS Istituto Nazionale dei Tumori

  Co-Author: Lukas B. Been, MD, PhD – Department of Surgical Oncology, University Medical Center Groningen, University of Groningen

  Co-Author: Robert J. Van Ginkel, MD, PhD – Department of Surgical Oncology, University Medical Center Groningen, University of Groningen

  Co-Author: Marc H.A. Bemelmans, MD, PhD (he/him/his) – Department of Surgery, Maastricht University Medical Center+, Maastricht

  Co-Author: Jos A. van der Hage, MD, PhD – Department of Surgery, Leiden University Medical Center

  Co-Author: Sander D.S. Dijkstra, MD, PhD – Department of Surgery, Leiden University Medical Center

  Co-Author: Silvia Stacchiotti (she/her/hers) – Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

  Co-Author: Cornelis Verhoef, N/A, MSc, MD, PhD – Erasmus Medical Center

  Co-Author: Alessandro Gronchi, MD, FSSO (he/him/his) – Fondazione IRCCS Istituto Nazionale dei Tumori
• 1:08 PM – 1:10 PM

  Q&A
• 1:10 PM – 1:18 PM

  A MULTICENTER RETROSPECTIVE EVALUATION OF THE FEASIBILITY AND RADIOLOGICAL AND CLINICAL OUTCOMES OF CRYO-ABLATION THERAPY FOR EXTRA-ABDOMINAL DESMOID
  

  Author: Alessandra Maleddu, MD – University of Colorado Anschutz Medical Campus

  Co-Author: Kenneth Cardona, MD, FACS – Winship Cancer Institute, Emory University

  Co-Author: Breelyn A. Wilky, MD (she/her/hers) – University of Colorado

  Co-Author: Andrea P. Espejo Freire, MD (she/her/hers) – University of Miami

  Co-Author: Steve Bandula, MD PhD MRCS FRCR – University College Hospital London NHS Foundation Trust

  Co-Author: Analie Morales, CNS – University College London Hospital NHS Foundation Trust

  Co-Author: Eve Merry – University College London Hospital NHS Foundation Trust

  Co-Author: Mesel Veli, MD – University College Hospital London NHS Foundation Trust

  Co-Author: Jessica M. Keilson, MD – Division of Surgical Oncology, Winship Cancer Institute, Emory University Hospital

  Co-Author: Melinda Yushak, MD – Division of Surgical Oncology, Winship Cancer Institute, Emory University Hospital

  Co-Author: David J Prologo, MD – Division of Surgical Oncology, Winship Cancer Institute, Emory University Hospital

  Co-Author: David C. Gimarc, MD – Department of Radiology, University of Colorado School of Medicine - Anschutz Medical Campus

  Co-Author: Mary J Underdown, MD – Department of Radiology, University of Colorado School of Medicine - Anschutz Medical Campus

  Co-Author: Shree Venkat, MD (she/her/hers) – University of Miami/Sylvester Comprehensive Cancer Center

  Co-Author: Emily Jonczak, MD (she/her/hers) – University of Miami/Sylvester Comprehensive Cancer Center

  Co-Author: Gina D'Amato, MD – University of Miami/Sylvester Comprehensive Cancer Center

  Co-Author: Palma Dileo, MD – University College London Hospitals NHS Foundation Trust
• 1:18 PM – 1:20 PM

  Q&A
• 1:20 PM – 1:28 PM

  EVALUATION OF METRONOMIC THERAPY AS A LOW-COST, SUSTAINABLE STANDARD OF CARE OPTION IN DESMOID FIBROMATOSIS: REAL WORLD DATA FROM A TERTEARY CARE CENTRE IN INDIA
  

  Author: Jyoti Bajpai, MD DM (she/her/hers) – Tata Memorial Centre

  Co-Author: Pritesh Munot, MD – Tata Memorial Centre

  Co-Author: Kishore Kota, Md, DM – Tata Memorial Centre

  Co-Author: Gaurav Gupta, MD, DM – Tata Memorial Centre

  Co-Author: Kunal Gala, MD – Tata Memorial Centre

  Co-Author: Aashish Gulia, MS – Tata Memorial Centre

  Co-Author: Bharat Rekhi:, MD (he/him/his) – Tata Memorial Centre

  Co-Author: Nehal Khanna, MD – Tata Memorial Centre

  Co-Author: Nitin Shetty, MD – Tata Memorial Centre

  Co-Author: Prabhat Ghanshyam Bhargava, MD, DM (he/him/his) – Tata Memorial Centre

  Co-Author: Sujay Srinivas, MD, DM – Tata Memorial Centre

  Co-Author: Vikas Ostwal, MD, DM – Tata Memorial Centre

  Co-Author: Vijay Patil, MD, DM – Tata Memorial Centre

  Co-Author: Vanita Noronha, MD – Tata Memorial Centre

  Co-Author: Suyash Kulkarni, MD – Tata Memorial Centre

  Co-Author: Siddharth Laskar, MD – Tata Memorial Centre

  Co-Author: Girish Chinnaswamy, MD – Tata Memorial Centre

  Co-Author: Kumar Prabhash, MD, DM – Tata Memorial Centre

  Co-Author: Sudeep Gupta, MD, DM – Tata Memorial Centre

  Co-Author: Shripad Banavali, MD – Tata Memorial Centre
• 1:28 PM – 1:30 PM

  Q&A
• 1:30 PM – 1:42 PM

  DEFI: A PHASE 3, RANDOMIZED, DOUBLE-BLIND TRIAL OF NIROGACESTAT VERSUS PLACEBO FOR PROGRESSING DESMOID TUMORS/AGGRESSIVE FIBROMATOSIS
  

  Author: Mrinal M. Gounder, MD – Memorial Sloan Kettering Cancer Center and Weill Cornell Medical Center

  Co-Author: Ravin Ratan, MD, M.Ed. – The University of Texas MD Anderson Cancer Center

  Co-Author: Thierry Alcindor, MD MSc – Dana-Farber Cancer Institute

  Co-Author: Patrick Schöffski, MD, MPH – Laboratory of Experimental Oncology, Department of Oncology, KU Leuven, Leuven Cancer Institute

  Co-Author: Winette T.A van der Graaf, MD, PhD – Netherlands Cancer Institute (NKI), Amsterdam, The Netherlands

  Co-Author: Breelyn A. Wilky, MD (she/her/hers) – University of Colorado

  Co-Author: Richard F. Riedel, MD – Duke Cancer Institute, Duke University Medical Center

  Co-Author: Allison Lim, PharmD – SpringWorks Therapeutics

  Co-Author: L. Mary Smith, PhD – SpringWorks Therapeutics

  Co-Author: Stephanie Moody, MS – PharPoint Research

  Co-Author: Steven Attia, D.O. – Mayo Clinic

  Co-Author: Sant P. Chawla, MD – Sarcoma Oncology Research Center

  Co-Author: Gina D'Amato, MD – University of Miami/Sylvester Comprehensive Cancer Center

  Co-Author: Noah Federman, MD (he/him/his) – David Geffen School of Medicine, UCLA Jonsson Comprehensive Cancer Center

  Co-Author: Priscilla Merriam, MD – Dana-Farber Cancer Institute

  Co-Author: Brian A. Van Tine, MD, PhD – Washington University School of Medicine

  Co-Author: Bruno Vincenzi, MD, PhD – Università Campus Bio-Medico di Roma

  Co-Author: Shivaani Kummar, MD, FACP (she/her/hers) – Oregon Health & Science University

  Co-Author: Bernd Kasper, MD, PhD – University of Heidelberg, Mannheim University Medical Center, Mannheim Cancer Center, Sarcoma Unit,
• 1:30 PM – 1:42 PM

  PSYCHOMETRIC PROPERTIES AND MEANINGFUL CHANGE THRESHOLDS (MCT) OF THE GOUNDER/DESMOID TUMOR RESEARCH FOUNDATION DESMOID SYMPTOM/IMPACT SCALE (GODDESS) AS ASSESSED IN THE PHASE 3 DEFI TRIAL
  

  Author: Mrinal M. Gounder, MD – Memorial Sloan Kettering Cancer Center and Weill Cornell Medical Center

  Co-Author: Thomas Atkinson, PhD – Memorial Sloan Kettering Cancer Center

  Co-Author: Timothy Bell, MHA – SpringWorks Therapeutics

  Co-Author: Christina Daskalopoulou, PhD – IQVIA

  Co-Author: Pip Griffiths, PhD – IQVIA

  Co-Author: Moriah Martindale (she/her/hers) – Memorial Sloan Kettering Cancer Center

  Co-Author: Allison Lim, PharmD – SpringWorks Therapeutics
• 1:42 PM – 1:45 PM

  Q&A
• 1:45 PM – 2:00 PM

  Bernd Kasper: "Summary of the Current Status of Fibromatosis Management"