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Northwestern University
Praveen Thumbikat, DVM, PhD
O'Connor Family Research Professor of Urology
Professor of Urology and Pathology
Northwestern University Feinberg School of Medicine
I am an academic researcher with a major focus on the immune basis of prostate disease in humans. We have a particular emphasis on chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), a debilitating medical condition characterized by dysuria and pelvic pain. My laboratory is also very interested in understanding the mechanism underlying inflammation of the human prostate and it's impact on benign disease and carcinogenesis. My laboratory utilizes comparative animal models that closely track human prostate disease as tools for translational research. Some specific areas of research interest are as follows - 1. Mechanisms in chronic pelvic pain: We are interested in understanding the mechanism of T cell mediated pain, the effectors of the pain pathway and measures to modulate Th1/Th17 immune response in animal models and ultimately in humans. 2. Mast cell mediated mechanisms in chronic pelvic pain and LUTS: We study the role of mast cells in pelvic pain and LUTS by focusing on neuroimmune mechanisms as well as fibrosis. Recently we have also been focused on developing unique pain models of prostate cancer bone metastasis as well as studying the role of the immune system in cancer-induced bone pain.
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Friday, May 13, 2022
9:30 AM – 11:30 AM