MP26-06: Prevalence of Kidney Stone Disease in U.S. Hispanic/Latino Adults: Findings from the Hispanic Community Health Study / Study of Latinos (HCHS/SOL)

Marcelino Rivera*, INDIANAPOLIS, IN, Jinsong Chen, Ana Ricardo, Chicago, IL, Robert Burk, Bronx, NY, Jianwen Cai, Chapel Hill, NC, Martha Daviglus, James Lash, Chicago, IL

Introduction: There is limited data available regarding the prevalence of kidney stone disease history in U.S. Hispanics/Latinos. The objective of this study is to investigate the prevalence of and risk factors for kidney stones among a diverse population of U.S. Hispanic/Latino adults.

Methods: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a community-based cohort of self-identified Hispanic/Latino adults from diverse backgrounds in the U.S. aged 18-74 years at enrollment through a multi-stage probability sampling design. We used data from 10,965 participants who completed a survey on self-reported history of kidney stone disease which was collected at a second study visit (2014-2017). Prevalence estimation accounted for the complex sampling design. Multivariable logistic regression was used to evaluate the association of risk factors with stone disease.

Results: The prevalence of kidney stone disease history was 10.6% (95% CI, 9.1%, 12.2%) in men and 7.8% (6.9%, 8.7%) in women. The prevalence varied by Hispanic/Latino background, and was lowest in persons of Mexican background (5.0%, [4.2%, 5.9%]) and highest in persons of Cuban background (16.2 [13.4%, 19.0%]. On multivariable logistic regression analysis, risk factors for prevalent kidney stone disease included older age and male sex (Table).

Conclusions: Kidney stone disease prevalence varied considerably by Hispanic/Latino background. Further investigation is required to determine reasons for these findings, as well as intrinsic and extrinsic causes of stone disease among Hispanic/Latino adults.

Source of Funding: The Hispanic Community Health Study / Study of Latinos is sponsored by the National Heart, Lung, and Blood Institute (NHLBI) and six other centers and Institutes of the National Institutes of Health (NIH).