(PO22-55-22) Cross-Sectional Associations of Fruit and Vegetable Intake With Coronary Artery Calcification and Pericardial Adiposity

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Presenting Author(s)

LR

Leigh Ann Richardson, MPH
– Graduate Research Assistant, University of Nevada, Las Vegas, N Las Vegas, Nevada, United States

Co-Author(s)

Arpita Basu, PhD, MPH, RD
– Associate Professor, University of Nevada, Las Vegas, Las Vegas, Nevada, United States
LC

Lung-Chang Chien
– University of Nevada, Las Vegas
AA

Amy C. Alman
– University of South Florida
JS

Janet K. Snell-Bergeon
– University of Colorado

Disclosure(s):

Leigh Ann Richardson, MPH: No relevant financial relationship(s) with ineligible companies to disclose.

Objectives: To examine the associations between fruit and vegetable (F&V) scores derived from the Mediterranean Diet (MedDiet) and Healthy Eating Index (HEI, 2015) with coronary artery calcification (CAC) and pericardial adiposity (PAT) in adults with and without type 1 diabetes (T1D).

Methods: We conducted a cross-sectional analysis of baseline data from the Coronary Artery Calcification in Type 1 Diabetes study [n=1255; T1D: n=563; non-DM: n=692]. Participants completed a validated food frequency questionnaire, a physical examination, and fasting (12h overnight fast) biochemical analyses. CAC and PAT were measured using electron beam computed tomography. Logistic regression models examined associations of F&V scores with CAC (presence or absence) and linear regression models were applied to PAT analyses. Model 1 was adjusted for age, sex and diabetes status, model 2 added total calories, and model 3 added BMI and lipids (LDL and HDL-cholesterol).

Results: F&V scores had no associations with CAC in any of these models. In models 1 and 2, a one-point increase in the MedDiet-derived total fruit score was associated with a significant -1.79% (95% CI: (-0.03, -0.01); p-value=0.0001) decrease in PAT. In model 3, a one-point increase in the MedDiet-derived total fruit score was associated with a borderline significant decrease of -0.74% (95% CI: (-0.01, 0.00); p-value=0.054) in PAT. In models 1 and 2 for the HEI-derived total fruit score, a one-point increase in the total fruit score was associated with a significant -3.22% (95% CI: (-0.05, -0.01); p-value=0.0012) decrease in PAT. In model 3 for the HEI-derived total fruit score, there was no significant association between the HEI-derived total fruit score and PAT (p-value=0.140).

Conclusions: Baseline analyses show MedDiet and HEI-derived total fruit scores maintained a significant to borderline significant inverse relationship with PAT, but F&V scores were not associated with presence of CAC.

Funding Sources: NIH and ADA