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Video ViewAttendees 51

Pharmacometrics & Pharmacokinetics (PMK)

Special Populations (SPO)

Early Career (EC)

Student & Trainee (ST)

Poster Walk: Maternal & Pediatric Therapeutic Optimization

Wednesday, March 16, 2022

5:30 PM – 6:00 PM ET

Chair(s)

Angela J. James, PhD

Vice President, Head of Clinical Pharmacology
MacroGenics, Inc.
Laura B. Ramsey, PhD

Associate Professor
Cincinnati Children's Hospital Medical Center

Poster Presenter(s)

Yumi Cleary

Senior Principal Scientist
F. Hoffmann-La Roche Ltd.
Valentina Shakhnovich, MD

Physician-Scientist
Children's Mercy - Kansas City
Nori Smeets, MD

MD PhD student
Radboud University Medical Center
Tajhia L. Whigham, PharmD

Post-Doctoctoral Research Associate
University of North Carolina at Chapel Hill

Session Schedule

5:30 PM - 5:32 PM ET
Introduction
Angela J. James, PhD and Laura B. Ramsey, PhD

5:32 PM - 5:36 PM ET
PW-007 - OFF-LABEL, BUT ON EVIDENCE? THE LEVEL OF EVIDENCE OF PEDIATRIC PHARMACOTHERAPY
Nori Smeets, MD

5:36 PM - 5:40 PM ET
PW-006 - INFLUENCE OF HEPATIC STEATOSIS, IN THE ABSENCE OF FIBROSIS, ON CYP3A4-MEDIATED CLEARANCE OF MIDAZOLAM IN CHILDREN WITH OBESITY
Valentina Shakhnovich, MD

5:40 PM - 5:44 PM ET
PW-008 - INCORPORATION OF PLACENTAL TRANSPORT IN PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODELS TO PREDICT METFORMIN (MET) UMBILICAL CORD CONCENTRATION (UCC) AT TERM IN PREGNANT WOMEN WITH GESTATIONAL DIABETES (GDM)
Tajhia Whigham, BS, PharmD

5:44 PM - 5:48 PM ET
PW-005 - ESTIMATION OF IN VIVO FMO3 ONTOGENY BY MECHANISTIC POPULATION PHARMACOKINETIC MODELLING OF RISDIPLAM IN INFANTS, CHILDREN AND ADULTS WITH SPINAL MUSCULAR ATROPHY
Yumi Cleary, MSc

5:48 PM - 6:00 PM ET
Live Q&A
All Speakers