Senior Research Fellow
Agios Pharmaceuticals, Inc.
Dr. Chandra Prakash is a Senior Research Fellow in Drug Metabolism, Pharmacokinetics and Clinical Pharmacology department at Agios, Cambridge, MA. He obtained his Ph.D. in synthetic organic chemistry. He held several academic appointments prior to joining the pharmaceutical industry. He worked for sixteen years at Pfizer Global Research and Development, Groton, CT and six years at Biogen, Cambridge where he managed a metabolism group. He joined Agios in June 2015.
For the last 30 years, Dr. Prakash has been involved in the drug metabolism and clinical pharmacology studies to support drug discovery, development and registration. His research is primarily focused on the development and utilization of novel approaches and techniques which include in vitro methods using human and animal hepatic cellular and subcellular systems, recombinant human drug metabolizing enzymes, sensitive analytical technologies and in silico computational models to assess the metabolism and toxicological aspects of the new chemical entities. He is the author of more than 288 manuscripts, book chapters, presentations and patents. He also coedited five volumes of Handbook of Metabolic Pathways of Xenobiotics. He served as the editor-in-chief of the Journals “Current Drug Metabolism” and "Drug Metabolism Letters" (2000-2015) and editorial board member of Annals of Medicinal Chemistry and Research, Current Biotechnology and journal of Pharmaceutics. He organized/chaired several national and international scientific meetings related to drug metabolism and toxicity.