Mayo Clinic
Thanh Thanh L. Nguyen, BA, is a PhD graduate student in Dr. Weinshilboum’s Pharmacogenomics Laboratory at the Mayo Clinic, Rochester, Minnesota. Her thesis project focuses on using drugs as probes to help understand the function of single nucleotide polymorphisms (SNP) that have been associated with a disease and/or drug response phenotype in genome-wide association studies (GWAS). Specifically, she utilizes a series of high-throughput genomic techniques to characterize so-called “pharmacogenomic-eQTLs,” that is, SNPs associated with alternations in gene expression but only in the presence of a drug, hormone, or exogenous chemical. She previously received training in neuroimaging at the Dartmouth Geisel School of Medicine, and neuromodulation in the Mayo Clinic Neural Engineering Laboratory. Thanh’s career goal is to be part of a collaborative, multidisciplinary team of scientists and clinicians, where the combination of genomic medicine and artificial intelligence can help to advance our understanding of the nature of common complex diseases such as psychiatric and neurological diseases, so that novel therapeutics can be devised for the alleviation of patient suffering. Thanh enjoys reading widely on literature, the arts and philosophy. She also likes to travel and learn about different cultures, as she has a come a long way from her birth place in Moscow, Russia, to Hanoi, Vietnam, and then to the U.S. where she has pursued her undergraduate and graduate education.