PW-006 - INFLUENCE OF HEPATIC STEATOSIS, IN THE ABSENCE OF FIBROSIS, ON CYP3A4-MEDIATED CLEARANCE OF MIDAZOLAM IN CHILDREN WITH OBESITY.

V. Shakhnovich^1,2,3, S. Abdel-Rahman¹, S. Chan^1,4, N. Mardis^1,2, N. Artz^1,2, Y. Chhonker⁵, D. Murry⁵, C. Friesen^6,7, V. Williams¹, S. Leeder¹; ¹Children's Mercy Hospital, Kansas City, MO, USA, ²University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA, ³Center for Children's Healthy Lifestyles and Nutrition, Kansas City, MO, USA, ⁴University of Missouri-Kansas City School of Medicine, Kansas City, MO, , ⁵University of Nebraska, Omaha, NE, USA, ⁶University of Kansas, Kansas City, KS, USA, ⁷Children's Mercy Kansas City, Kansas City, MO, USA.