PW-001 - METABOLOMICS-INFORMED-PHARMACOGENOMIC-BASED PREDICTIONS OF RESPONSE TO COMBINATION ANTIDEPRESSANT THERAPIES: A MACHINE LEARNING APPROACH WITH CROSS-TRIAL REPLICATION.

C. Grant¹, J. Joyce¹, R. Kaddurah-Daouk², M. Skime¹, J. Biernacka¹, T. Mayes³, T. Carmody³, P. Croarkin¹, L. Wang¹, R. Weinshilboum¹, W. Bobo¹, M. Trivedi³, A. Athreya¹; ¹Mayo Clinic, Rochester, MN, USA, ²Duke University Medical Center, Durham, NC, USA, ³University of Texas Southwestern Medical Center, Dallas, TX, USA.