Poster Session

(14) Comparative Evaluation of Demineralized Bone Matrix and Bioactive Glass Putty in the Treatment of Periodontal Intrabony Defects using Cone Beam Computed Tomography

Lead Author(s)

DD

Dr. Gopalakrishnan Dharmarajan, BDS, MDS, PhD

Dean, Professor & Head(Chair) - Department of Periodontology
Dr. D.Y. Patil Dental College & Hospital, Dr. D.Y. Patil Vidyapeeth, Pune
Pune, Maharashtra, India

Co-Author(s)

RJ

Ravichandra Juluri, DDS, MS

Periodontist and Oral Implantologist Faculty OSF Hospital GPR Program
OSF Hospital, Peoria, Illinois
Springfield, Illinois, United States

Introduction: In order to achieve an optimal periodontal regeneration, the bone graft material used should be porous in nature which facilitates influx of blood vessels into the pores and helps in faster integration. The current study is designed to evaluate and compare Demineralized Bone Matrix and Bioactive Glass Putty and in the treatment of human periodontal intrabony defects using cone beam computed tomography.

Methods: 10 pairs of periodontal intrabony defects with a total of 20 sites in 10 patients were randomly divided into Control Site A and Test Site B according to split mouth design.
Control site A – 10 sites were treated with open flap debridement followed by the placement of Demineralized Bone Matrix.
Test site B - 10 sites were treated with open flap debridement followed by placement of Bioactive Glass Putty.
Clinical parameters recorded at baseline and 9 months post-operative were Plaque index (PI), Gingival index (GI), Probing pocket depth (PPD), Clinical attachment level (CAL) and Gingival marginal level (GML). Radiological Parameters assessed were crestal height of the Defect, Base of the Defect & Osseous Defect at baseline and 9 months.

Results: Both groups showed significant improvement clinically in PI, GI, PPD and CAL and radiologically in the Base of the Defect & Osseous
Defect from baseline to 9 months. The group(Test site B) treated with Bioactive Glass Putty demonstrated a significant percentage of defect fill than the group(Control Site A) treated with Demineralized Bone Matrix (p>0.05).

Conclusions: The above 9 month results suggest that the group(Test site B) treated with Bioactive Glass Putty had significantly greater hard tissue fill, clinical attachment gain & greater probing depth reduction when compared to the group(Control Site A) treated with Demineralized Bone Matrix and both materials improved above baseline.

Lead Author's Contributions to the Research Project. : Lead Author was responsible for the conceptualisation, design and execution of the entire study.