Background and Objectives Patients with severe periodontal disease may have pathological tooth movement, often resulting in secondary occlusal trauma and esthetic disturbance. We report here a case for whom the combination of orthodontic treatments not only met the esthetic requirements but also improved the periodontal disease. Materials and Methods A 62-year-old female patient came to the hospital with a chief complaint of halitosis. Root bifurcation lesions in #24, #27, and #47, and vertical bone defects in #23, #24, #37, and #47 were observed by radiography. In addition, #24 and #27 showed degree III and degree II agitations, respectively. After examination, a diagnosis of extensive chronic periodontitis, Stage III-Grade C was made. Results The results of the reevaluation showed significant improvement in BOP and PPD. Vertical bone defects in #23 and #37 were treated with periodontal tissue regeneration therapy using enamel matrix derivatives. The root bifurcation lesion in #27 was addressed with a trisection. After periodontal surgical treatment, orthodontic treatment was performed for the vertical bone defect in #47. Significant improvement in periodontal pathology was achieved after the treatment. Conclusion In this case, orthodontic treatment was able to improve secondary occlusal trauma and esthetic disorders. This suggested that the use of orthodontic treatment for periodontal disease can improve periodontal disease as well as esthetic disorders.