Anesthesia Resident Purdue University West Lafayette, Indiana
The goal of this study was to evaluate electroencephalography (EEG) changes associated with propofol anesthesia in dogs using the Sedline® monitor.
Methods: Six two-year-old dogs were each given propofol constant rate of infusions (CRI) for induction (1 mg kg minute for 10 minutes), followed by a decremented maintenance dose of 2.4 mg kg, 1.6 mg kg-1, and 0.8 mg kg-1 minute-1 over 45 minutes, with 15 minutes for each dose. The EEG data, including Patient State Index (PSI, 0-cortical silence, 100-awake), burst suppression ratio (SR), and spectral edge frequency 95% (SEF95) were obtained continuously until the dogs assumed sternal recumbency. The dogs were intubated and ventilated. Repeated measures ANOVA were used to compare the mean index values of each of the anesthetic stages. All values are expressed as mean ± SD.
