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Scientific Session

Oncology

The Science Behind SINE Class Drugs: Novel Small Molecules for Oncology

On Demand

CE: .75

Sponsored by

Primary Presenter(s)

DB

David Bruyette, DVM, DACVIM (SAIM)

Chief Medical Officer
Anivive Lifesciences
Long Beach, California, United States

Slides Proceedings/Handout

Selective inhibition of nuclear export (SINE) class drugs are small molecules recently introduced to both human and veterinary oncology. This course will explore the mechanism of action, demonstrated in vitro effects, and clinical indications of this novel class of drugs. It will also explore how SINE class drugs introduce a new way to think about managing cancer and how they may be integrated into the treatment of several neoplastic diseases.

Learning Objectives:

Understand the mechanism of action of SINE class drugs
Understand why the mechanism of action has broad reaching implications for the future of cancer treatments
Understand the in vitro effects and how they may be clinically applicable
Become familiar with the currently available SINE class drugs and their current and potential indications in the treatment of cancer.