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Professor of Psychiatry
Harvard Medical School
Alkermes (Products/Services: No) (Advisory Board)Burrage Capital (Products/Services: No) (Consultant)Circular Genomics (Products/Services: No) (Advisory Board, Stockholder/Ownership Interest (excluding diversified mutual funds))Genomind (Products/Services: No) (Advisory Board)Psy Therapeutics (Products/Services: No) (Advisory Board, Stockholder/Ownership Interest (excluding diversified mutual funds))Vault Health (Products/Services: No) (Consultant, Stockholder/Ownership Interest (excluding diversified mutual funds))
Roy Perlis, MD MSc is Associate Chief for Research in the Department of Psychiatry and Director of the Center for Quantitative Health at Massachusetts General Hospital. He is Professor of Psychiatry at Harvard Medical School and holds the Ronald I. Dozoretz, MD Endowed Chair. He serves as Associate Editor for Neuroscience at JAMA's new open-access journal, JAMA Network - Open. Dr. Perlis graduated from Brown University, Harvard Medical School and Harvard School of Public Health, and completed his residency, chief residency, and clinical/research fellowship at MGH before joining the faculty.
Dr. Perlis's research is focused on identifying predictors of treatment response in brain diseases, and applying these biomarkers to develop novel treatments. He directs two complementary laboratory efforts, one focused on patient-derived cellular models and one applying machine learning to large clinical and databases. His laboratory identified the first risk genes for major depressive disorder, and led the first genomewide association studies of lithium response as well as suicide risk. More recently, they identified the first patient-derived cellular model of schizophrenia liability.
Dr. Perlis has authored more than 350 articles reporting original research, in journals including JAMA, NEJM, Nature Genetics, Nature Neuroscience, the British Medical Journal, and the American Journal of Psychiatry. His research has been supported by awards from NIMH, NHGRI, NHLBI, NICHD, NCCIH, and NSF, among others. In 2010 Dr. Perlis was awarded the Depression and Bipolar Support Alliance's Klerman Award; he now serves as a scientific advisor to the DBSA.
