Associate professor Korea university medical college Seoul, Republic of Korea
Research Objectives: To investigate the relationship between muscle strength and osteoporosis and the effect on health-related quality of life (QOL) in Korea
Design: This is an observational study. We used the data from the Korea National Health and Nutrition Examination Survey (KNHANES) from 2015 to 2018.
Setting: The general community
Participants: We analyzed the data of 13,966 people over 40-year-old provided by the KNHANES 2015-2018.
Interventions: N/A
Main Outcome Measures: We applied multiple logistic regression analysis to investigate the relationship between handgrip strength (HGS) with the presence of osteoporosis and health-related QOL that was assessed by the European Quality of Life Scale-Five dimensions (EQ-5D).
Results: Females diagnosed with osteoporosis showed significantly weaker HGS than those without osteoporosis. However, there was no significant difference in males. People with weak HGS generally showed lower EQ-5D values than those with strong HGS. The quality of life of those diagnosed with osteoporosis was significantly reduced in both the strong and weak HGS groups. We calculated the odds ratios of each dimension of EQ-5D of osteoporosis patients according to the HGS based on the values of healthy people with strong HGS. Among the strong HGS group, osteoporosis patients showed the odds ratios of 1.855 (95% CI; 1.504-2.287) in mobility, 1.390 (0.924-2.093) in self-care, 1.503 (1.143-1.978) in usual activity, 1.484 (1.250-1.761) in pain/discomfort, and 1.518 (1.189-1.939) in anxiety/depression. In osteoporosis patients with weak HGS, the odds ratios were 2.675 (2.082-3.439) in mobility, 2.625 (1.814-3.800) in self-care, 2.359 (1.765-3.152) in usual activity, 1.964 (1.559-2.474) in pain/discomfort, and 1.754 (1.341-2.294) in anxiety/depression.
Conclusions: Our study confirmed that low HGS with the presence of osteoporosis is correlated with low health-related QOL. Thus, HGS may be a practical factor to predict QOL in people with osteoporosis.
Author(s) Disclosures: We have no conflicts of interest to disclose.
Learning Objectives:
Upon completion, participants will be able to learn that muscle strength is an important factor affecting the quality of life.
Upon completion, participants will be able to learn that handgrip strength is one of the critical indicators reflecting muscle strength and quality of life in osteoporosis patients.
Upon completion, participants will be able to comprehend the importance of strengthening exercise to improve the quality of life in patients with osteoporosis.
.jpg)
