Weill Cornell Medical College
New York, NY, United States
Dr. Pascual obtained her MD from the Complutense University in Madrid. She did a Residency in Pediatrics at the Hospital 12 de Octubre in Madrid and a Fellowship in Pediatric Rheumatology at UT Southwestern Medical Center in Dallas, TX, where she also did a post-doctoral fellowship in Immunology and Microbiology under the mentorship of Dr. J. Donald Capra. Her laboratory is focused on understanding the pathogenesis, finding biomarkers to guide therapeutic interventions and identifying therapeutic targets for human inflammatory and autoimmune diseases, including Systemic Lupus Erythematosus (SLE), various forms of Arthritis, as well as immune responses to a broad variety of infections and vaccinations. She is Program Director of an NIAID-funded Autoimmunity Center of Excellence and a NIAMS-funded Center for Lupus Research. Pioneering studies from her laboratory identified the role of dendritic cells and Interferon in SLE, and of cytokines such as IL1 in Systemic-onset Juvenile Arthritis, which has led to successful therapeutic interventions in this disease. She also developed a personalized approach to identify molecular drivers of disease activity in pediatric SLE patients. This approach enabled the stratification of patients into seven major molecular subgroups, which might lead to improved design of clinical trials for this disease.
Disclosure information not submitted.
Monday, November 14, 2022
5:00 PM – 6:00 PM Eastern Time
