Jane H. Buckner, MD

Benaroya Research Institute at Virginia Mason
Seattle, WA, United States

Jane Buckner is the President of the Benaroya Research Institute at Virginia Mason (BRI), Affiliate Professor of Immunology at the University of Washington, and Affiliate Professor of Medicine, Division of Rheumatology also at the University of Washington. Dr. Buckner’s interdisciplinary research combines genetics, immunology and clinical medicine to advance our understanding of the causes of autoimmune diseases. Her research is focused on understanding the mechanisms through which self-tolerance is lost in human autoimmune disease. The diseases studied in the laboratory include type 1 diabetes, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus and relapsing polychondritis. The research goal is to expand our understanding of each disease by identifying the common features that cause them. Her research group has approached this question through the study of genetic risk variants associated with autoimmunity, analysis of regulatory and effector adaptive responses in samples from patients with autoimmune disease and targeted analysis of autoreactive CD4 T cells from patients with autoimmunity.

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Presentation(s):

• Deep Immune Phenotyping Reveals Similarities Between Aging, Down's Syndrome, and Autoimmunity

  Sunday, November 13, 2022
  12:30 PM – 12:50 PM Eastern Time