Poster Session A

Pediatric autoimmune diseases: Kawasaki disease, juvenile dermatomyositis and juvenile localized scleroderma

Format: Virtual Only

(0034–0044) Pediatric Rheumatology – Basic Science Poster

Saturday, November 12, 2022

1:00 PM – 3:00 PM Eastern Time

Location: Virtual Poster Hall

All of the relevant financial relationships listed for faculty have been mitigated.

Poster abstract session.

Presentations:

1:00 PM – 3:00 PM Eastern Time

Association of Anti-Tropomyosin Alpha-4 Autoantibodies with Cutaneous Manifestations in Juvenile Dermatomyositis
Abstract Poster Presenter: Rie Karasawa, MD, PhD – St. Marianna University School of Medicine
1:00 PM – 3:00 PM Eastern Time

Anti-Peroxiredoxin 6 and Anti- Myosin Light Polypeptide 6 Autoantibodies with Interstitial Lung Disease and Severe Disease in Juvenile Dermatomyositis
Abstract Poster Presenter: Rie Karasawa, MD, PhD – St. Marianna University School of Medicine
1:00 PM – 3:00 PM Eastern Time

Patient-specific and Disease-related Determinants for Cardiovascular Disease (CVD) Risk Stratification in the APPLE (Atherosclerosis Prevention in Paediatric Lupus Erythematosus) Clinical Trial Cohort
Abstract Poster Presenter: Junjie Peng, BSc, MSc – University College London
1:00 PM – 3:00 PM Eastern Time

Dual (and Dueling) Fibroblast Differentiation Is Integral to the Pathogenesis of Anti-Ro Mediated Congenital Heart Block and Provides a Novel Biomarker of Severity
Abstract Poster Presenter: Christina Firl, BA – NYU Grossman School of Medicine
1:00 PM – 3:00 PM Eastern Time

STING Antagonist (IFM4490) Inhibits STING Activation and STING Dependent Signal Transduction in Patients with STING-associated Vasculopathy with Onset in Infancy (SAVI)
Abstract Poster Presenter: Sachin Gaurav, II, PhD – NIH-NIAID
1:00 PM – 3:00 PM Eastern Time

Type I and Type II Interferon and NF-κB-Response Gene Scores and Serum Cytokine Levels in Patients with Various Systemic Autoinflammatory Diseases
Abstract Poster Presenter: Sophia Park, BS – NIAID
1:00 PM – 3:00 PM Eastern Time

Plasma Proteomic Signatures in Juvenile Dermatomyositis Highlight Novel Proteins and a Protein Module That Associate with Skin and Global Disease Activity
Abstract Poster Presenter: Marianne Kerski, MD – University of Michigan
1:00 PM – 3:00 PM Eastern Time

Modeling Juvenile Dermatomyositis with Engineered Human Skeletal Muscle: Effects of Type I Interferonβ and Janus Kinase Inhibitors
Abstract Poster Presenter: Lauren Covert, MD – Duke University
1:00 PM – 3:00 PM Eastern Time

The Pathogenic Role of Lymphatic Vessels in Autoimmune Valvular Carditis
Abstract Poster Presenter: Amritha Yellamilli, MD, PhD – Stanford University School of Medicine
1:00 PM – 3:00 PM Eastern Time

Non-invasive Tape Strip Gene Expression Profiling of Lesional Juvenile Dermatomyositis Skin Identifies Immunoregulatory Module That Associates with Skin, Muscle and Global Disease Activity
Abstract Poster Presenter: Jessica L. Turnier, MD, MS – University of Michigan
1:00 PM – 3:00 PM Eastern Time

Follistatin-like Protein 1 Alters T Cell Receptor Signaling Dynamics in Vitro, While Expression in Vivo Correlates with Disease and Deficiency Increases Acute Inflammation in a Mouse Model of Kawasaki Disease
Abstract Poster Presenter: Mark Gorelik, MD – Columbia University School of Medicine