12S143: Abstracts: Innate Immunity (0554–0557)

Abstract Moderator(s)

• 

  J. Michelle Kahlenberg, MD, PhD

  University of Michigan
  Ann Arbor, MI, United States

  Disclosure(s): Ample Biosolutions: Advisor or Review Panel Member (Ongoing); AstraZeneca: Consultant (Ongoing); Aurinia Pharmaceuticals: Advisor or Review Panel Member (Ongoing); Bristol-Myers Squibb(BMS): Advisor or Review Panel Member (Ongoing), Grant/Research Support (Ongoing); EMD-Serano: Consultant (Ongoing); Gilead: Consultant (Ongoing); GlaxoSmithKlein(GSK): Consultant (Ongoing); Horizon Therapeutics: Consultant (Ongoing); Q 32 Bio: Grant/Research Support (Terminated); Rome Therapeutics: Grant/Research Support (Ongoing); Ventus Therapeutics: Consultant (Ongoing), Grant/Research Support (Ongoing)
• SR

  Siba Raychaudhuri, MD

  UC Davis, School of Medicine/ VA Medical Center, Sacramento
  Davis, CA, United States

  Disclosure(s): AbbVie: Consultant (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); Amgen: Consultant (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); Celgene: Consultant (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); Eli Lilly: Consultant (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); Janssen: Consultant (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); Novartis: Consultant (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); Pfizer: Consultant (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); Sun: Consultant (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing); UCB: Consultant (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing)

Oral abstract session.

Presentations:

• 5:00 PM – 5:10 PM Eastern Time

  Loss of Synovial Tissue Macrophage Homeostasis Precedes Rheumatoid Arthritis Clinical Onset
  

  Presenting Author: Megan Hanlon, PhD, BSc – Molecular Rheumatology
• 5:10 PM – 5:15 PM Eastern Time

  Q&A
  
• 5:15 PM – 5:25 PM Eastern Time

  Heterogeneity in Origin and Function of Distinct Human Synovial-tissue Dendritic Cells in Health, Active Rheumatoid Arthritis (RA) and RA in Disease Remission
  

  Presenting Author: Domenico Somma, PhD – School of infection and immunity
• 5:25 PM – 5:30 PM Eastern Time

  Q&A
  
• 5:30 PM – 5:40 PM Eastern Time

  Immune Checkpoint VISTA Regulates Type I Interferon (IFN-I) Production and Controls UV Light Triggered Skin IFN-I Response
  

  Presenting Author: Zachary Peters, BA – Dartmouth
• 5:40 PM – 5:45 PM Eastern Time

  Q&A
  
• 5:45 PM – 5:55 PM Eastern Time

  VEXAS Syndrome Is Characterized by Blood and Tissues Inflammasome Pathway Activation and Monocyte Dysregulation
  

  Presenting Author: Benjamin Terrier, MD, PhD – Cochin Hospital
• 5:55 PM – 6:00 PM Eastern Time

  Q&A