13S108: Abstracts: Pediatric Rheumatology – Basic Science (0566–0569)

Abstract Moderator(s)

• AP

  Anna Patrick, MD, PhD

  Vanderbilt University Medical Center
  Nashville, TN, United States

  Disclosure(s): No financial relationships with ineligible companies to disclose
• 

  Randy Cron, MD, PhD

  University of Alabama at Birmingham
  Birmingham, AL, United States

  Disclosure(s): Novartis: Consultant (Terminated); Pfizer: Advisor or Review Panel Member (Ongoing); Sironax: Consultant (Terminated); SOBI: Advisor or Review Panel Member (Ongoing), Consultant (Ongoing), Grant/Research Support (Ongoing), Speaker/Honoraria (includes speakers bureau, symposia, and expert witness) (Ongoing)

Oral abstract session.

Presentations:

• 8:00 AM – 8:10 AM Eastern Time

  SARS-CoV-2-Specific T Cell Responses in Multisystem Inflammatory Syndrome in Children
  

  Presenting Author: Ki Pui Lam, PhD – Division of Immunology, Boston Childrens Hospital, Harvard Medical School
• 8:10 AM – 8:15 AM Eastern Time

  Q&A
  
• 8:15 AM – 8:25 AM Eastern Time

  Gain-of-Function Mutations in Lyn Kinase Cause a Novel Autoinflammatory Disease with Small Vessel Vasculitis and Liver Fibrosis
  

  Presenting Author: Adriana Almeida de Jesus, MD, PhD – NIAID, NIH
• 8:25 AM – 8:30 AM Eastern Time

  Q&A
  
• 8:30 AM – 8:40 AM Eastern Time

  The Absence of Blk Leads to Increased Inflammation in a Murine Model of Kawasaki Disease
  

  Presenting Author: Melissa Kleinau, BSc – University of Toronto
• 8:40 AM – 8:45 AM Eastern Time

  Q&A
  
• 8:45 AM – 8:55 AM Eastern Time

  Cytokine Storm Susceptibility Factors IL-18 and Cytotoxic Impairment Converge on Pathologic CD8 T-cell Hyperactivation
  

  Presenting Author: Scott Canna, MD – Children's Hospital of Philadelphia
• 8:55 AM – 9:00 AM Eastern Time

  Q&A