(1727–1749) T Cell Biology and Targets in Autoimmune and Inflammatory Disease Poster

Poster abstract session.

Presentations:

• 1:00 PM – 3:00 PM Eastern Time

  Increased CD39+FoxP3+CD4+ Regulatory T Cells in Early Rheumatoid Arthritis Provide a Slot for Prompt Initiation of Methotrexate and Serve as Early Biomarkers of Clinical Response
  

  Abstract Poster Presenter: Maria-Eugenia Miranda-Carus, MD – Hospital Universitario La Paz
• 1:00 PM – 3:00 PM Eastern Time

  Changes in the Number and Phenotype of Citrullinated-Antigen Specific T Cells Correlate with Treatment Outcome in Seropositive Rheumatoid Arthritis
  

  Abstract Poster Presenter: Eddie James, PhD – Benaroya Research Institute at Virginia Mason
• 1:00 PM – 3:00 PM Eastern Time

  Deep Immune Profiling of Cytotoxic T Cells (CTL) from Patients with Ankylosing Spondylitis Revealed a Subset of CTL Co-Expressing PD-1 and TIGIT That Resists Immune Exhaustion
  

  Abstract Poster Presenter: Michael Tang, PhD – University Health Network
• 1:00 PM – 3:00 PM Eastern Time

  Mass Spectrometry-Based HLA Peptidomics Analysis Reveals Both Expected and Novel Citrullinated Antigen Targets in Rheumatoid Arthritis
  

  Abstract Poster Presenter: Eddie James, PhD – Benaroya Research Institute at Virginia Mason
• 1:00 PM – 3:00 PM Eastern Time

  BATF Represses BIM Expression to Sustain the T Cell Anergy Program
  

  Abstract Poster Presenter: Daniel Mueller, MD – University of Minnesota
• 1:00 PM – 3:00 PM Eastern Time

  Increased Frequency of Highly Differentiated T Effector Memory Cells Re-expressing CD45RA (Temra) and Cytomegalovirus Seropositivity Are Associated with Persistent Disease Specifically Refractory to Anti-TNF Therapy in Rheumatoid Arthritis
  

  Abstract Poster Presenter: Su-Ann Yeoh, MBBS – University College London
• 1:00 PM – 3:00 PM Eastern Time

  SLAMF4+ CCR5+ Effector Memory CD4+ T Cells Are Polyfunctional, Resistant to Exhaustion, and Expanded in Rheumatoid Arthritis
  

  Abstract Poster Presenter: jerome Biton, PhD – Université Sorbonne Paris Nord, Inserm UMR1125
• 1:00 PM – 3:00 PM Eastern Time

  T Cell-Macrophage Interactions Play a Critical Role in a Mouse Model of Histidyl-tRNA Synthetase-Induced Myositis
  

  Abstract Poster Presenter: Dana Ascherman, MD – University of Pittsburgh
• 1:00 PM – 3:00 PM Eastern Time

  Systemic Sclerosis-Associated Class II HLA Alleles Restrict the Diversity of the CDR3 and the T Cell Receptor Repertoire in African American Patients
  

  Abstract Poster Presenter: Urvashi Kaundal, PhD – National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH)
• 1:00 PM – 3:00 PM Eastern Time

  Novel Human Class II MHC Tetramers Detect Rare, Self-Reactive CD4+ T Cells Relevant to Mixed Connective Tissue Disease
  

  Abstract Poster Presenter: Shawn Mahmud, MD, PhD – University of Minnesota
• 1:00 PM – 3:00 PM Eastern Time

  Granzyme K Elicits a New Pathway for Complement Activation in RA Synovium
  

  Abstract Poster Presenter: Anna Helena Jonsson, MD, PhD – Brigham and Women's Hospital
• 1:00 PM – 3:00 PM Eastern Time

  Identification of Sjögren’s Disease-Associated T Cell Receptors Through Deep Sequencing and Single-Cell Transcriptomics
  

  Abstract Poster Presenter: Ananth Aditya Jupudi, -None- – University of Oklahoma Health Sciences Center
• 1:00 PM – 3:00 PM Eastern Time

  Clonally Expanded Cytotoxic CD8⁺ T Cells Recognize Citrullinated Antigens in ACPA⁺ Rheumatoid Arthritis
  

  Abstract Poster Presenter: Jae-Seung Moon, PhD – Stanford University
• 1:00 PM – 3:00 PM Eastern Time

  IL-23 Signaling Induces Autoimmune Disease Genes in Mucosal-Associated Invariant T Cells
  

  Abstract Poster Presenter: Lars Rogge, PhD – Institut Pasteur
• 1:00 PM – 3:00 PM Eastern Time

  In Vitro Response to Disease Modifying Antirheumatic Drugs Link Molecular Drug Target with Synovial Transcriptional Signature
  

  Abstract Poster Presenter: Tue Kragstrup, MD, PhD – Aarhus University
• 1:00 PM – 3:00 PM Eastern Time

  Characterization of T Cell Subsets in the Synovium of Chronic Inflammatory Joint Diseases
  

  Abstract Poster Presenter: Aleksandra Khmelevskaia, MSc – Center of Experimental Rheumatology, University Hospital of Zurich
• 1:00 PM – 3:00 PM Eastern Time

  Single-Cell Characterization of the TCR Repertoire Across Tissue and Blood in Rheumatoid Arthritis
  

  Abstract Poster Presenter: Garrett Dunlap, BS – Harvard University
• 1:00 PM – 3:00 PM Eastern Time

  WITHDRAWN
• 1:00 PM – 3:00 PM Eastern Time

  Mutated Nod2 Controls T Cell Function and Promotes Uveitis in a Blau Syndrome Mouse Model
  

  Abstract Poster Presenter: Leah Huey, BS – Oregon Health & Science University
• 1:00 PM – 3:00 PM Eastern Time

  Shared Epitope Allomorphs Directly Influence Antigen-specific T-cell Responses in RA
  

  Abstract Poster Presenter: Ravi Kumar, PhD – Karolinska Institutet
• 1:00 PM – 3:00 PM Eastern Time

  Identification of Immune Cell Types in the Peripheral Blood of Rheumatoid Arthritis Patients Associated with Susceptibility and Response to Treatment
  

  Abstract Poster Presenter: Sebastien Viatte, MD, PhD – The University of Manchester
• 1:00 PM – 3:00 PM Eastern Time

  Immune Responses to mRNA Vaccines Against SARS-CoV-2 in Patients with Immune-mediated Inflammatory Rheumatic Diseases
  

  Abstract Poster Presenter: Cristiana Sieiro Santos, MD – Complejo Asistencial Universitario de León
• 1:00 PM – 3:00 PM Eastern Time

  Effects of Excess IL-18 in Mixed Inflammatory Environments
  

  Abstract Poster Presenter: Vinh Dang, BS – Children's Hospital of Philadelphia