14M123: Gout Is an Autoinflammatory Metabolic Disease

Monday, November 14, 2022

10:30 AM – 11:30 AM Eastern Time

Location: Terrace Ballroom II&III

CE: 1

All of the relevant financial relationships listed for faculty have been mitigated.

Moderator(s)

Michael Pillinger, MD

New York University Grossman School of Medicine
New York,, NY, United States

Disclosure(s): Fortress: Consultant (Ongoing); Hikma: Grant/Research Support (Ongoing); Horizon: Consultant (Ongoing), Grant/Research Support (Ongoing); Sobi: Consultant (Ongoing)

This session will address the autoinflammatory nature of gout and highlight it as one of the truly IL-1 β -mediated diseases. Increasing knowledge on the inflammatory mechanisms of gout has implications for disease management. These engaging talks will review the state of the science regarding the immunology, clinical manifestations, and treatments of acute gout flares and anti-inflammatory prophylaxis as an integral part of gout treatment.

Learning Objectives:

Describe the mechanisms underlying gouty inflammation
Understand the role of IL-1 and the NLRP3 inflammasome in gouty inflammation
Discuss current therapies and emerging drugs in the pipeline for the treatment of acute gout flares and anti-inflammatory prophylaxis

Presentations:

10:30 AM – 10:50 AM Eastern Time

IL-1 β Induces Gouty Inflammation
Speaker: Charles Dinarello, BA – university of colorado
10:50 AM – 11:10 AM Eastern Time

Treatment of Acute and Chronic Gouty Inflammation an Update
Speaker: Naomi Schlesinger, MD – Rutgers Robert Wood Johnson Medical School
11:10 AM – 11:30 AM Eastern Time

Q&A