14M169: Mediators of Organ Damage or Fibrosis

Monday, November 14, 2022

5:00 PM – 6:00 PM Eastern Time

Location: Room 204

CE: 1

All of the relevant financial relationships listed for faculty have been mitigated.

Moderator(s)

Laura Donlin, PhD

Hospital for Special Surgery
New York, NY, United States

Disclosure(s): No financial relationships with ineligible companies to disclose

Faculty will cover novel insights into the pathology of organ damage and molecular pathways controlling fibrosis. Attendees will acquire critical knowledge related to the role of fibroblasts in rheumatic diseases.

Learning Objectives:

Review key cell states driving organ damage or fibrosis in chronic inflammatory diseases
Discuss the application of single-cell transcriptomics to define pathological cell states in disease tissues
Define molecular mechanisms that underly tissue damage or fibrosis in inflammatory diseases

Presentations:

5:00 PM – 5:15 PM Eastern Time

Single-cell Deconstruction of Systemic Sclerosis
Speaker: Robert Lafyatis, MD – University of Pittsburgh
5:15 PM – 5:20 PM Eastern Time

Q&A
5:20 PM – 5:35 PM Eastern Time

Joint Inflammation or Damage? Fibroblasts Decide!
Speaker: Adam Croft, PhD, MRCP – University of Birmingham
5:35 PM – 5:40 PM Eastern Time

Q&A
5:40 PM – 5:55 PM Eastern Time

Pathogenic Myeloid Cells in Lupus Nephritis
Speaker: Paul Hoover, MD, PhD – Brigham and Women's Hospital
5:55 PM – 6:00 PM Eastern Time

Q&A