12S104: Cytoplasmic Sensing During Aging and Autoimmunity

Saturday, November 12, 2022

11:00 AM – 11:45 AM Eastern Time

Location: Room 121

CE: 0.75

All of the relevant financial relationships listed for faculty have been mitigated.

Moderator(s)

AM

Ann Marshak-Rothstein, PhD

UMass Chan Medical School
Worcester, MA, United States

Disclosure(s): No financial relationships with ineligible companies to disclose

The session will present updates on cytoplasmic sensors as they relate to aging and disease with some focus on sensors that negatively regulate autoimmunity (when knocked out, disease is worsened).

Learning Objectives:

Understand how alterations in cytoplasmic sensors contribute to autoimmunity
Learn how aging alters cytoplasmic sensing and thus disease response

Presentations:

11:00 AM – 11:15 AM Eastern Time

Tissue-specific Initiators of Autoinflammation/Autoimmunity in Mice Expressing STING Gain-of-Function Mutations
Speaker: Ann Marshak-Rothstein, PhD – UMass Chan Medical School
11:15 AM – 11:30 AM Eastern Time

Cytoplasmic Sensor Pathways That Do Not Promote Autoimmunity
Speaker: Mays Mohammed Salih, BS – University of California Santa Cruz
11:30 AM – 11:45 AM Eastern Time

Q&A