Metabolic bone disease

12S148: Molecular Mechanisms of Osteoporosis

Moderator(s)

• MN

  Mary Nakamura, MD

  UCSF/SFVAHCS
  San Francisco, CA, United States

  Disclosure(s): No financial relationships with ineligible companies to disclose
• JC

  Julia Charles, MD, PhD

  Brigham and Women's Hospital
  Boston, MA, United States

  Disclosure(s): Ultragenyx: Advisor or Review Panel Member (Ongoing)

Osteoporosis remains a highly prevalent condition that results from multiple mechanisms. This session will highlight recent studies examining the molecular mechanisms that lead to osteoporosis.

Presentations:

• 5:00 PM – 5:15 PM Eastern Time

  Marrow Adipogenic Lineage Precursors: A Master Regulator of Bone Metabolism
  

  Speaker: Ling QIN, PhD – University of Pennsylvania
• 5:15 PM – 5:20 PM Eastern Time

  Q&A
  
• 5:20 PM – 5:35 PM Eastern Time

  The Role of the Gut Microbiome Induced Th17 Cells Migrating to Bone to Drive Post-Menopausal Osteoporosis
  

  Speaker: Roberto Pacifici, MD – Emory University
• 5:35 PM – 5:40 PM Eastern Time

  Q&A
  
• 5:40 PM – 5:55 PM Eastern Time

  Megakaryocytes Promote Osteoclastogenesis in Age-Related Osteoporosis
  

  Speaker: Melissa Kacena, PhD – Indiana University School of Medicine
• 5:55 PM – 6:00 PM Eastern Time

  Q&A