12S120: Edmund L. Dubois, MD, Memorial Lecture

Saturday, November 12, 2022

12:30 PM – 1:00 PM Eastern Time

Location: Terrace Ballroom IV

CE: 0.50

All of the relevant financial relationships listed for faculty have been mitigated.

Moderator(s)

KD

Kimberly DeQuattro, MD

University of Pennsylvania
Media, PA, United States

Disclosure(s): No financial relationships with ineligible companies to disclose

Dr. Rao will discuss the recent effort that use detailed immunoprofiling to define prominent features of lymphocyte dysregulation in blood and tissue samples from patients with SLE, including the recognition of expanded populations of T peripheral helper cells, T follicular helper cells, and CD11c+ age-associated B cells. He will discuss implications for these findings and their potential utility as cellular biomarkers to detect and track SLE-associated adaptive immune cell activation for use in clinical practice.

Learning Objectives:

Summarize the use of immunoprofiling to identify features of lymphocyte activation in SLE patients
Describe lymphocyte populations that are commonly altered in the circulation of patients with SLE
Discuss approaches to use alterations in circulating lymphocyte composition as biomarkers of immune activation in SLE

Presentations:

12:30 PM – 12:50 PM Eastern Time

Edmund L. Dubois, MD, Memorial Lecture
Speaker: Deepak A. Rao, MD, PhD – Brigham and Women's Hospital
12:50 PM – 1:00 PM Eastern Time

Q&A