11F102: Basic and Clinical Research Conference

Moderator(s)

• 

  Peter Grayson, MD, MSc

  National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH)
  Chevy Chase, MD, United States

  Disclosure(s): No financial relationships with ineligible companies to disclose
• 

  Jill Norris, PhD, MPH

  Colorado School of Public Health
  Denver, CO, United States

  Disclosure(s): No financial relationships with ineligible companies to disclose

Presentations:

• 9:00 AM – 9:35 AM Eastern Time

  Understanding Somatic Mutations and their Detection: Detection of Somatic Mutations and Somatic Mutations in Normal Tissue
  

  Speaker: Peter Campbell, PhD – Wellcome Sanger Institute
• 9:35 AM – 9:45 AM Eastern Time

  Q&A
  
• 9:45 AM – 10:30 AM Eastern Time

  Understanding Somatic Mutations and their Detection: Importance of Germline Genetics in Rheumatology
  

  Speaker: Ivona Aksentijevich, MD – 100
• 10:30 AM – 10:40 AM Eastern Time

  Q&A
  
• 10:55 AM – 11:20 AM Eastern Time

  Examples from Other Disciplines: Somatic Mutations in IBD
  

  Speaker: Sigurgeir Olafsson, PhD – Wellcome Sanger Institute
• 11:20 AM – 11:30 AM Eastern Time

  Q&A
  
• 11:30 AM – 11:55 AM Eastern Time

  Examples from Other Disciplines: Clonal Hematopoiesis of Indeterminate Potential
  

  Speaker: Alexander Bick, MD, PhD – Vanderbilt University
• 11:55 AM – 12:05 PM Eastern Time

  Q&A
  
• 12:05 PM – 12:30 PM Eastern Time

  Examples from Other Disciplines: Somatic Mutations in Immunodeficiency
  

  Speaker: Megan Cooper, MD, PhD – Washington University School of Medicine
• 12:30 PM – 12:40 PM Eastern Time

  Q&A
  
• 1:30 PM – 1:55 PM Eastern Time

  Examples from Rheumatology: Discovery of the VEXAS Syndrome
  

  Speaker: David Beck, MD, PhD – New York University
• 1:55 PM – 2:05 PM Eastern Time

  Q&A
  
• 2:05 PM – 2:30 PM Eastern Time

  Examples from Rheumatology: Somatic Mutations Shape Autoantibody Response
  

  Speaker: Joanne Reed, PhD – Westmead Institute for Medical Research
• 2:30 PM – 2:40 PM Eastern Time

  Q&A
  
• 2:40 PM – 3:05 PM Eastern Time

  Examples from Rheumatology: Somatic Mutations in Erdheim Chester Disease
  

  Speaker: Juvianee Estrada-Veras, MD – National Human Genome Research Institute
• 3:05 PM – 3:15 PM Eastern Time

  Q&A
  
• 3:30 PM – 4:05 PM Eastern Time

  How to Integrate into Research and Clinical Practice: Integration of Genetics into Multiomics Discovery in Rheumatology
  

  Speaker: Fan Zhang, PhD – The University of Colorado
• 4:05 PM – 4:15 PM Eastern Time

  Q&A
  
• 4:15 PM – 5:00 PM Eastern Time

  How to Integrate into Research and Clinical Practice: Role of Somatic Mutations in Future Disease Taxonomy in Rheumatology
  

  Speaker: Daniel Kastner, MD, PhD – National Human Genome Research Institute
• 5:00 PM – 5:15 PM Eastern Time

  Q&A
  
• 5:15 PM – 5:30 PM Eastern Time

  Closing Remarks