Poster Session E - Tuesday Afternoon
Category: IBD
Stephen B. Hanauer, MD
Northwestern University
Chicago, Illinois
| 5mg/Kg q8 weeks | 10 mg/Kg q8 weeks | Overall |
Clearance (L/day) |
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ATI negative
| O: 0.223±0.001 (n=5,076) B: 0.232±0.004 (n=399) Fold: 1.04; p=0.059 | O: 0.251±0.001 (n=2,480) B: 0.257±0.005 (n=179) Fold: 1.02; p=0.176 | O: 0.232±0.001 (n=7556) B: 0.239±0.003 (n=578) Fold: 1.03; p=0.033 |
ATI positive
| O: 0.432±0.003 (n=1,015) B: 0.439±0.009 (n=115) Fold: 1.02; p=0.196 | O: 0.443±0.006 (n=305) B: 0.428±0.028 (n=21) Fold: 1.01; p=0.712 | O: 0.434±0.003 (n=1320) B: 0.437±0.009 (n=136) Fold: 1.01; p=0.487 |
Overall
| O: 0.258±0.110 (n=6,091) B: 0.278±0.120 (n=514) Fold: 1.08; p< 0.01 | O: 0.272±0.097 (n=2785) B: 0.275±0.094 (n=200) Fold: 1.01; p=0.375 | O: 0.262±0.001 (n=8876) B: 0.277±0.004 (n=714) Fold: 1.06; p< 0.001 |
IFX (µg/mL) |
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ATI negative
| O: 8.7±0.1 (n=5,076) B: 8.3±0.4 (n=399).95 Fold: 0.95; p=0.538 | O: 11.6±0.2 (n=2,480) B: 10.7±0.6 (n=179) Fold: 0.92; p=0.272 | O: 9.7±0.1 (n=7556) B: 9.2±0.3 (n=578) Fold: 0.95; p=0.024 |
ATI positive
| O: 1.3±0.1 (n=1,015) B: 1.2±0.2 (n=115) Fold: 0.92; p=0.994 | O: 2.3±0.2 (n=305) B: 3.2±1.0 (n=21) Fold: 1.4; p=0.626 | O: 1.5±0.1 (n=1320) B: 1.5±0.3 (n=136) Fold: 1.00; p=0.818 |
Overall
| O: 7.5±0.1 (n=6,091) B: 6.7±0.3 (n=514) Fold: 0.89; p< 0.01 | O: 10.6±0.2 (n=2785) B: 9.9±0.6 (n=200) Fold: 0.93; p=0.547 | O: 8.5±0.1 (n=8876) B: 7.6±0.3 (n=714) Fold: 0.89; p< 0.001 |