Poster Session D - Tuesday Morning
Category: Liver
Reza Saeidi, MD
Beaumont Hospital/RCSI
Dublin, Dublin, Ireland
| Cirrhosis N=33 | Healthy controls N=15 | P-value |
Age (Mean, SD) | 59, 2 | 45, 2 | 0.0001 |
Male Gender (n) | 22 (66%) | 7 (46%) |
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Aetiology | ALD (n=22) NASH (n=6) AIH (n=1) PBC (n=1) Cryptogenic (n=1) NASH/ASH/A1AT (n=1) HCV/HIV/ALD (n=1) |
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MELD (mean, IQR) | 11, 7-12 |
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Clinical Ascites | Female: 0 Male: 9 (41%) |
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Liver frailty index, Frail | Female: 5 (45%) Male: 5 (23%) |
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Active alcohol drinking | 10 (30%) |
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Smoker | 16 (48%) | 3 (20%) |
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BMI kg/m2 (Mean, SD) | 29.44, 1.2 | 26.65, 0.73 | 0.06 |
Albumin (mean, IQR) | 39, 36-43 |
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Bilirubin (mean, IQR) | 20, 9-41 |
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INR (mean, IQR) | 1.2, 1.02-1.04 |
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Platelet (mean, IQR) | 143, 94-183 |
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ALT (mean, IQR) | 31, 21-36 |
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Waist circumference (cm) {Mean, SD} | 101, 2 | 91.6, 3 | 0.01 |
Waist circumference, excluding ascites (cm) {Mean, SD} | 103.6, 3 | 91.6, 3 | 0.006 |
TMT (cm) {mean, SD} | 3.69, 0.2 | 4.4, 0.2 | 0.02 |
Vastus intermedius (VI) {Mean, SD} | 1.45, 0.9 | 2.05, 0.1 | 0.0006 |
Rectus femoris (RF) {mean, SD} | 1.9, 0.8 | 2.2, 0.1 | 0.05 |
SF (cm) {mean, SD} | 1.42, 0.2 | 1.19, 0.1 | 0.26 |
Skeletal muscle mass (Kg) {Mean, SD} | 24.2, 1.12 | 25.92, 1.55 | 0.39 |
Fat mass (Kg) Mean, SD | 29, 3 | 22, 2 | 0.04 |
handgrip strength (Kg) {Mean, SD} | 25, 2 | 38, 3 | 0.0005 |
Sit-to-stand (sec) {Mean, SD} | 14.36, 1.24 | 8.84, 0.76 | 0.0005 |
Gait speed (sec) {Mean, SD} | 5.64, 1.42 | 2.78, 0.5 | 0.05 |
Physical activity level (Mean, SD) | 1.75, 0.03 | 1.92, 0.03 | 0.0001 |