Award: Outstanding Research Award in the GI Bleeding Category
Award: Presidential Poster Award
Sandeep Bagla, MD1, Alex Pavidapha, MD1, Abin Sajan, MD2, Rachel Piechowiak, MD1, Pratik Desai, MD3, Atul Marathe, MD4, Kenneth Josovitz, MD5 1Hemorrhoid Centers, Falls Church, VA; 2Columbia University Irving Medical Center, New York, NY; 3Potomac Urology, Alexandria, VA; 4Gastro Health, Woodbridge, NY; 5Gastro Health, Woodbridge, VA
Introduction: Endovascular hemorrhoidal artery embolization has emerged as an analogous therapy to Doppler-guided ligation. The purpose of this study was to evaluate the safety and efficacy of outpatient transarterial embolization for symptomatic refractory internal hemorrhoids.
Methods: One hundred and twenty-six patients with symptomatic bleeding internal hemorrhoids refractory to prior treatment (e.g., banding, dietary/lifestyle modifications) were treated between August 2021 and May 2022 (62 men and 64 women). The average age was 58.3 +/- 15.8 years with an average Goligher's hemorrhoid grade of 2.2. Patients underwent superior and/or middle rectal artery embolization to the target arteries demonstrating abnormal vascular blush of the hemorrhoidal cushion with spherical embolic particles (500 or 600 micron) and/or microcoils (2-6 mm). Patients were discharged two hours post-procedure and were evaluated at baseline and 1-month for the following standardized outcomes: hemorrhoid related pain (HRP, 0-10), hemorrhoid symptoms score (HSS, 5-20), quality of life (QoL, 0-4), French bleeding score (FBS, 0-9), and hemorrhoid grade (0-4).
Results: Femoral (121/126) or radial access (5/126) was performed and successful embolization of the superior and/or middle rectal artery was achieved in 126/126 (100%) patients. Statistically significant improvements in all outcomes were reported at follow-up (baseline vs 1 month): HRP (4.6 vs 1.7, p < 0.001), HSS (10.2 vs 7.1, p < 0.001), QoL (2.4 vs 0.7, p < 0.001), FBS (3.9 vs 1.5, p < 0.001), and hemorrhoid grade (2.0 vs 1.6, p = 0.03). One minor adverse event was reported: post-procedural peri-anal pain that required topical cream, which resolved soon after treatment. No major adverse events were reported.
Discussion: Hemorrhoidal artery embolization is a safe and effective outpatient treatment for refractory symptomatic internal hemorrhoids.
Disclosures:
Sandeep Bagla indicated no relevant financial relationships.
Alex Pavidapha indicated no relevant financial relationships.
Abin Sajan indicated no relevant financial relationships.
Rachel Piechowiak indicated no relevant financial relationships.
Pratik Desai indicated no relevant financial relationships.
Atul Marathe indicated no relevant financial relationships.
Kenneth Josovitz indicated no relevant financial relationships.
Sandeep Bagla, MD1, Alex Pavidapha, MD1, Abin Sajan, MD2, Rachel Piechowiak, MD1, Pratik Desai, MD3, Atul Marathe, MD4, Kenneth Josovitz, MD5. E0310 - Safety and Efficacy of Hemorrhoidal Artery Embolization in Patients Refractory to Conservative Management, ACG 2022 Annual Scientific Meeting Abstracts. Charlotte, NC: American College of Gastroenterology.