C0086 - There Is No Difference in Frequency or Outcome of Colon Ischemia Based Upon the Season of Presentation

Ahmad Nawaz, MD¹, Rabia Rizwan, MD¹, Abdelkader Chaar, MD¹, Houssam Alnahhas, MD, MPH², Karthik Gnanapandithan, MD³, Muhammad Sohail Mansoor, MD⁴, Abdul Qadir Bhutta, MD⁵, Adil Bhutta, MD⁶, Marc Fenster, MD⁷, Olga Aroniadis, MD, MSc, FACG⁸, Savio John, MD⁹, Lawrence Brandt, MD, MACG¹⁰, Paul Feuerstadt, MD, FACG^11
1Yale University School of Medicine, New Haven, CT; ²Syria Public Health Network, London, England, United Kingdom; ³Mayo Clinic Florida, Jacksonville, FL; ⁴GI Specialists of Georgia, Marietta, GA; ⁵SUNY Upstate Syracuse University Hospital, Syracuse, NY; ⁶Yale New Haven Health, Hamden, CT; ⁷Jacobi Medical Center, Bronx, NY; ⁸Stony Brook Medicine, Stony Brook, NY; ⁹State University of New York Upstate University Hospital, Syracuse, NY; ¹⁰Montefiore Medical Center, Bronx, NY; ¹¹PACT Gastroenterology Center and Yale University School of Medicine, New Haven, CT

Introduction: Colon Ischemia (CI) is the most common ischemic injury to the gastrointestinal tract. Studies from Asia have shown a seasonal variation of CI with an increased incidence in the summer months. Our study hypothesizes that in a United States population focusing within a northeastern group of hospitals, where there is a significant variation in the seasonal climate, there is a seasonal variation in the incidence and outcome for CI.

Methods: We conducted a multicenter retrospective cohort study of pts admitted with biopsy-proven CI admitted to Yale-New Haven Hospital, Montefiore Medical Center, Weiler Medical Center, and SUNY-Upstate Medical Center from 2005 through 2017. For each patient, demographics, medical co-morbidities, treatments, and outcomes were recorded. Using a meteorological definition of seasons, we subdivided the population into the onset of CI during the spring (SP-CI; March to May), summer (SU-CI; June to Aug), fall (FA-CI; Sept to Nov), and winter (WI-CI; Dec to Feb). We then compared the seasonal cohorts. Our primary outcome was incidence of CI based upon the season. The secondary outcomes included combination of 30-day colectomy and mortality (i.e., poor outcome), segmental involvement, intensive care unit (ICU) requirements, length of the hospital stay (LOS), 30-day readmission and recurrence.

Results: A total of 685 pts met inclusion criteria. There were no differences in incidence based upon season: CI-SP (27%), CI-SU ( 24.5%), CI-FA ( 22%) and CI-WI ( 26.4%). There were also no differences with regards to age, gender or BMI. No differences were observed in the presentation, medical comorbidities, Charlson Comorbidity Index or treatment patterns among the four groups. When considering outcomes, 30-day colectomy was observed 10.3%, 8.2%, 9.2% and 11.1% in the CI-SP, CI-SU, CI-FA and CI-WI group, respectively (p=0.84). There were also no significant differences when considering 30-day mortality or poor-outcome. LOS, ICU requirements, segmental involvement, 30-day readmission and 30- day recurrence were not significantly different between the four groups (table1).

Discussion: Our study showed no difference in the distribution of biopsy-proven cases of CI based upon seasonal change. This is in contrast to Asian based studies. It is possible that the severity of the cases considered in our study are different than the Asian studies and that mild cases might have a seasonal variation that are less likely to undergo a colonoscopy to confirm the diagnosis.



Disclosures:


Ahmad Nawaz, MD¹, Rabia Rizwan, MD¹, Abdelkader Chaar, MD¹, Houssam Alnahhas, MD, MPH², Karthik Gnanapandithan, MD³, Muhammad Sohail Mansoor, MD⁴, Abdul Qadir Bhutta, MD⁵, Adil Bhutta, MD⁶, Marc Fenster, MD⁷, Olga Aroniadis, MD, MSc, FACG⁸, Savio John, MD⁹, Lawrence Brandt, MD, MACG¹⁰, Paul Feuerstadt, MD, FACG¹¹. C0086 - There Is No Difference in Frequency or Outcome of Colon Ischemia Based Upon the Season of Presentation, ACG 2022 Annual Scientific Meeting Abstracts. Charlotte, NC: American College of Gastroenterology.