Poster Session C - Monday Afternoon
Category: Esophagus
Pedro Cortes, MD
Mayo Clinic
Jacksonville, FL
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| Association with being symptomatic | |||
| Median (IQR) or fraction (%) of patients | Unadjusted analysis | Multivariable analysis | |||
| Symptomatic N = 59 | Asymptomatic N = 257 | OR (95% CI) | p-value | OR (95% CI) | p-value |
Age at diagnosis, years (10 year increase) | 60.0 (43.9-68.5) | 57.3 (41.5-67.3) | 1.08 (0.91-1.29) | 0.41 | 1.00 (0.83-1.21) | 0.83 |
Male | 25/59 (42.4%) | 85/257 (33.1%) | 1.49 (0.83-2.65) | 0.18 | 1.12 (0.60-2.11) | 0.73 |
Weight, kg (10 kg increase) | 78.9 (63.3-90.5) | 76.5 (62.5-90.7) | 0.98 (0.86-1.11) | 0.77 | 0.98 (0.86-1.12) | 0.78 |
Height, cm (10 cm increase) | 167 (160.0-175.0) | 167 (160.0-173.0) | 1.14 (0.89-1.46) | 0.29 | 1.13 (0.88-1.48) | 0.37 |
o Height > 158 cm | 54/59 (91.5%) | 205/254 (80.7%) | 2.58 (1.07-7.70) | 0.03 | 2.50 (1.01-7.54) | 0.034 |
Body mass index, kg/m2 (5 kg/m2 increase) | 25.8 (22.4-30.3) | 26.7 (22.9-32.4) | 0.93 (0.76-1.05) | 0.46 | 0.98 (0.86-1.11) | 0.74 |
Obesity | 16/58 (27.6%) | 83/254 (32.7%) | 0.78 (0.42-1.48) | 0.45 | 1.09 (0.56-2.15) | 0.80 |
White race | 53/59 (89.8%) | 206/251 (82.1%) |
2.19 (0.96-5.93)
| 0.09 | 1.95 (0.83-5.38) | 0.15 |
Ethnicity, Hispanic/Latino | 3/59 (5.1%) | 21/257 (8.2%) | 0.60 (0.17-2.09) | 0.42 | 0.93 (0.25-3.50) | 0.92 |
Family History, negative | 57/59 (96.6%) | 230/257 (89.5%) | 3.35 (0.77-14.48) | 0.10 | 2.29 (0.63-14.78) | 0.28 |
Type of CT scan performed o Chest CT Angiogram o Contrast Chest CT |
31/59 (52.5%) 28/59 (47.5%) |
122/257 (47.8%) 133/257 (52.2%) |
1.00 (reference) 0.83 (0.47-1.46) |
0.52 |
1.00 (reference) 0.61 (0.33-1.12) |
0.11 |
Diameter at origin max, mm (10 mm increase) | 17 (14.0-19.0) | 16 (13.0-18.0) | 1.21 (0.63-2.34) | 0.57 | 0.93 (0.42-2.07) | 0.86 |
Diameter at origin min, mm (10 mm increase) | 14 (11.5-17.0) | 13 (11.0-16.0) | 1.32 (0.65-2.67) | 0.45 | 0.98 (0.43-2.27) | 0.97 |
Cross-sectional area at origin, mm2 (50 mm2 increase) | 166 (122.5-240.5) | 150 (109.0-215.0) | 1.03 (0.90-1.18) | 0.67 | 0.98 (0.84-1.15) | 0.81 |
Diameter at crossing of esophagus max, mm (10 mm increase) | 12 (10.0-13.5) | 11 (10.0-13.0) | 1.03 (0.50-2.10) | 0.94 | 0.76 (0.25-2.34) | 0.63 |
Diameter crossing of esophagus min, mm (10 mm increase) | 10 (9.0-12.0) | 10 (8.0-12.0) | 1.23 (0.56-2.69) | 0.60 | 0.76 (0.25-2.34) | 0.45 |
Cross-sectional area at crossing of esophagus, mm2 (50 mm2increase) | 88 (68.0-120.0) | 85 (59.0-120.0) | 1.06 (0.83-1.36) | 0.63 | 1.03 (0.76-1.35) | 0.85 |
o Area > 60 mm | 52/59 (88.1%) | 189/257 (73.5%) | 2.67 (1.23-6.70) | 0.02 | 2.39 (1.08-6.06) | 0.046 |
Distance between ARSA and trachea, mm (1 mm increase) | 5 (2.5-6.0) | 5 (3.0-6.0) | 0.91 (0.81-1.02) | 0.11 | 0.85 (0.75-0.97) | 0.02 |
o Distance | 53/59 (89.8%) | 213/257 (82.9%) | 1.83 (0.79-4.97) | 0.19 | 2.24 (0.88-5.73) | 0.09 |
Angle of Proximate ARSA with the Arch, degrees (10 degree increase) | 110 (90.0-121.0) | 101 (73.0-118.0) | 1.09 (0.99-1.21) | 0.08 | 1.08 (0.98-1.20) | 0.14 |
o Angle > 108 degrees | 32/59 (54.2%) | 96/257 (37.4%) | 1.99 (1.12-3.54) | 0.02 | 1.90 (1.06-3.42) | 0.032 |
Presence of Kommerell aneurysm | 2/59 (3.4%) | 4/257 (1.6%) | 2.22 (0.40-12.41) | 0.36 | 2.26 (0.39-13.07) | 0.36 |
Presence of atherosclerotic plaque within ARSA | 23/59 (39.0%) | 77/257 (30.0%) | 1.49 (0.83-2.69) | 0.18 | 1.31 (0.69-2.47) | 0.41 |
Severity of atherosclerotic plaque o Mild o Moderate o Severe |
14/23 (60.9%) 6/23 (26.1%) 3/23 (13.0%) |
49/77 (63.6%) 23/77 (29.9%) 5/77 (6.5%) |
1.00 (reference) 0.91 (0.31-2.68) 2.10 (0.45-9.89) |
0.87 0.35 |
1.00 (reference) 0.73 (0.23-2.32) 1.82 (0.35-9.38) |
0.59 0.47 |
Presence of thrombus within ARSA | 0/59 (0.0%) | 3/257 (1.2%) | NA | 1.00 | NA | NA |
Presence of proximal esophagus dilation | 0/59 (0.0%) | 23/257 (8.9%) | NA | 0.01 | NA | NA |