Introduction: Inflammatory pseudotumors (IPT) are rare non-malignant lesions. Lungs are the most common locations of origin. They remain extremely rare in the colon.
Case Description/Methods: An 80-year-old lady underwent colonoscopy for recent diverticulitis. Physical examination and laboratory workup were unremarkable. A two-month prior Computer tomography (CT) scan revealed sigmoid diverticulosis with segmental wall thickening, suggestive of acute diverticulitis. Colonoscopy demonstrated a large, ulcerated, non-circumferential, nonobstructing, nonbleeding mass in the sigmoid colon. She developed bowel perforation and underwent exploratory laparotomy with sigmoid and left colectomy, and colostomy. Histopathology revealed numerous abscess sinuses within the colonic wall, extending from the diverticula. Extensive acute and chronic inflammation was also present. There was no evidence of dysplasia or malignancy.
Discussion: Inflammatory pseudotumors may have clinical and radiological features similar to malignancies, and may even recur after resection, however, malignant transformation is rare.
Figure: Figures 1a and 1b: Colonoscopy demonstrating a large, ulcerated, non-circumferential, nonobstructing, nonbleeding mass in the sigmoid colon
Disclosures:
Syed Mustajab Ahmed indicated no relevant financial relationships.
Praneet Wander indicated no relevant financial relationships.
Syed Mustajab Ahmed, MD, Praneet Wander, MD. B0307 - A Large Inflammatory Pseudotumor of the Sigmoid Colon Causing Perforation, ACG 2022 Annual Scientific Meeting Abstracts. Charlotte, NC: American College of Gastroenterology.
