Shari Dermer, PhD, Roderick Smith, MS, Erin Jones, MS Medscape Education, New York, NY
Introduction: Ulcerative colitis (UC) is characterized by uncontrolled immune response in the intestinal mucosa. Sphingosine 1 phosphate (S1P) receptor modulators are a new treatment for moderate to severely active UC. The aim of this study was to examine the effect of online continuing medical education (CME) with enhanced animation graphics to increase knowledge on oral S1P-targeted treatments for UC.
Methods: Gastroenterologists (N=89) participated in an online CME activity that featured video discussion, synchronized slides, and whiteboard animation. Educational effect was assessed using a repeated-pair design with pre-/post-assessment including 3 multiple choice questions that assessed knowledge and 1 question that assessed confidence. A paired samples t-test was used for significance testing on overall average number of correct responses and for confidence rating, and a McNemar’s test was conducted at the learning theme level (5% significance level, P < .05). The activity launched on August 31, 2021; data were collected on November 15, 2021.
Results: Overall 52% of leaners improved knowledge regarding the mechanism of action (MOA) and on data for S1P receptor modulators. Improvements in knowledge and confidence pre/post education are reported: Mechanism of S1P modulators: There was a 125% relative increase (28%/63%, pre/post; p < .001) in knowledge on the MOA of S1P receptor modulators for the treatment of UC. 58% and 37% of learners increased or maintained, respectively, their confidence in their ability to describe S1P receptor modulators as a therapeutic target for UC. Data on S1P receptor modulators: There was a 15% relative increase (74%/85%, pre/post; p < .01) in knowledge regarding clinical data from trials of S1P receptor modulators. Safety and monitoring considerations: There was a 64% relative increase (33%/54%, pre/post; p < .001) in knowledge about safety considerations and monitoring associated with use of S1P receptor modulators in practice.
Discussion: Video-based CME with a whiteboard animation showing the MOA of S1P receptor modulators improved knowledge and confidence on the mechanism of S1P modulation in UC treatment, data, and safety considerations for S1P modulators. This study reveals the need for more education on the MOA of S1P modulation and safety considerations for their use in practice.
Reference: Sandborn WJ, et al. Sphingosine-1-Phosphate Modulators: An Emerging Target in Ulcerative Colitis. August 31, 2021. Available at: https://www.medscape.org/viewarticle/957485
Disclosures:
Shari Dermer indicated no relevant financial relationships.
Roderick Smith indicated no relevant financial relationships.
Erin Jones indicated no relevant financial relationships.
Shari Dermer, PhD, Roderick Smith, MS, Erin Jones, MS. D0402 - Online Animation-Enhanced CME Improves Knowledge on Sphingosine 1 Phosphate Receptor Modulation for the Treatment of Ulcerative Colitis, ACG 2022 Annual Scientific Meeting Abstracts. Charlotte, NC: American College of Gastroenterology.