D0613 - Outcomes of Endoscopic Sleeve Gastroplasty in the Elder Population

Tuesday, October 25, 2022

10:00 AM – 12:00 PM ET

Location: Crown Ballroom

Has Audio

Presenting Author(s)

MM

Maria Valeria Matteo, MD

Fondazione Policlinico Universitario A. Gemelli IRCCS
Vaglio Basilicata, Lazio, Italy

Award: Presidential Poster Award

Maria Valeria Matteo, MD¹, Vincenzo Bove, MD¹, Valerio Pontecorvi, MD¹, Martina De Siena, MD¹, Ciasca Gabriele, PhD¹, Massimiliano Papi, PhD¹, Giulia Giannetti, PhD¹, Chiara Massari, ², Nausicaa Antonini, ², Giorgio Carlino, MD³, Guido Costamagna, MD, PhD, FACG², Ivo Boskoski, MD, PhD²
¹Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Lazio, Italy; ²Fondazione Policlinico Gemelli IRCCS, Rome, Lazio, Italy; ³Univesrità degli studi dell'Aquila, L'Aquila, Abruzzi, Italy

Introduction: With the ageing of the population and the epidemic spread of obesity, the frequency of older individuals with obesity is steadily growing. To date, no data evaluating the use of endoscopic sleeve gastroplasty (ESG) in the elderly have been published. In this case series, we evaluate the short and medium-term outcomes of ESG in patients with obesity aged 65 years and older.

Methods: A retrospective analysis was done on a prospective database; patients aged 65 years and older were included in our analysis. EWL%, TBWL%, the Bariatric Analysis and Reporting Outcome System (BAROS) questionnaire and the presence of comorbidities were assessed.

Results: 18 patients aged 65 years and older underwent ESG between November 2017 and July 2021. The median age was 67 years and the mean baseline BMI was 41.2 kg/m 2 . After ESG the median TBWL% was 15.1%, 15.5%, and 15.5% at 6, 12 and 24 months, while the median %EWL was 39%, 37%, and 41% at 6, 12 and 24 months, respectively. The median BAROS score was 3.0, 3.4 and 2.5 at 6, 12, and 24 months, respectively. 6/12 patients with hypertension and 3/4 diabetic patients reduced or removed their medications within 12 months following ESG. 2/6 patients with OSA stopped therapy with CPAP. No adverse events were
recorded.

Discussion: According to our experience, ESG is a promising therapeutic option for elder individuals with obesity who fail non-invasive methods, and who refuse or are deemed not suitable for bariatric surgery because of age and comorbidities.

Variable	1 month *N=18**	3 months N=18	6 months N=18	12 months N=12	18 months N=10¹	24 months N =10¹	p-value #
EWL% Median (25%-75%)	21 (19-30)	36 (30-43)	39 (34-45)	37 (30-49)	44 (25-48)	41 (34-48)	0.034
TBWL% Median (25%-75%)	9.4 (7.4-11.8)	13.0 (11.6-15.3)	15.1 (10.9-18.8)	15.5 (10.5-19.6)	16.3 (9.3-22.1)	15.5 (9.6-21.6)	0.009
BAROS score Median (25%-75%)	2.6 (1,1-2.5)	2.6 (2.0-3.4)	3.0 (2.3-3.9)	3.4 (2.4-3.9)	3.0 (2.5-3.5)	2.5 (2.1-3.4)	0.2
* N = Number of patients #Kruskal-Wallis rank sum test BAROS: Bariatric Analysis and Reporting Outcome System; TBWL: total body weight loss; EWL: excess weight loss.

Disclosures:

Maria Valeria Matteo indicated no relevant financial relationships.

Vincenzo Bove indicated no relevant financial relationships.

Valerio Pontecorvi indicated no relevant financial relationships.

Martina De Siena indicated no relevant financial relationships.

Ciasca Gabriele indicated no relevant financial relationships.

Massimiliano Papi indicated no relevant financial relationships.

Giulia Giannetti indicated no relevant financial relationships.

Chiara Massari indicated no relevant financial relationships.

Nausicaa Antonini indicated no relevant financial relationships.

Giorgio Carlino indicated no relevant financial relationships.

Guido Costamagna indicated no relevant financial relationships.

Ivo Boskoski: Apollo Endosurgery – Consultant, grant holder.

Maria Valeria Matteo, MD¹, Vincenzo Bove, MD¹, Valerio Pontecorvi, MD¹, Martina De Siena, MD¹, Ciasca Gabriele, PhD¹, Massimiliano Papi, PhD¹, Giulia Giannetti, PhD¹, Chiara Massari, ², Nausicaa Antonini, ², Giorgio Carlino, MD³, Guido Costamagna, MD, PhD, FACG², Ivo Boskoski, MD, PhD². D0613 - Outcomes of Endoscopic Sleeve Gastroplasty in the Elder Population, ACG 2022 Annual Scientific Meeting Abstracts. Charlotte, NC: American College of Gastroenterology.