Poster Session E - Tuesday Afternoon
Category: IBD
Amy Guo, PhD
Ferring Pharmaceuticals
Parsippany, NJ
| RBX2660 | Placebo | ||||||
Component (Mean ± SD) | Baseline | Week 8 | Change from baseline | Unadjusted P-value | Baseline | Week 8 | Change from baseline | Unadjusted P-value |
Responders | ||||||||
Total | 43.7 ± 17.4 | 75.8 ± 18.3 | 32.1 ± 21.4 | < 0.001 * | 42.4 ± 20.3 | 70.1 ± 23.2 | 27.7 ± 19.8 | < 0.001 * |
Physical | 52.6 ± 21.1 | 84.2 ± 16.9 | 31.7 ± 22.8 | < 0.001 * | 49.9 ± 22.7 | 79.2 ± 21.6 | 29.3 ± 23.2 | < 0.001 * |
Mental | 32.7 ± 16.8 | 66.4 ± 22.0 | 33.7 ± 24.1 | < 0.001 * | 33.0 ± 20.5 | 60.1 ± 27.0 | 27.0 ± 21.4 | < 0.001 * |
Social | 53.5 ± 23.6 | 80.2 ± 21.3 | 26.6 ± 27.9 | < 0.001 * | 49.3 ± 26.5 | 73.6 ± 27.8 | 24.3 ± 27.3 | < 0.001 * |
Non-responders | ||||||||
Total | 61.5 ± 16.7 | 76.3 ± 5.9 | 14.8 ± 16.4 | 0.423 | 59.0 ± 31.0 | 57.2 ± 35.0 | -1.8 ± 25.6 | 0.854 |
Physical | 78.0 ± 14.9 | 91.1 ± 4.7 | 13.1 ± 19.3 | 0.423 | 62.5 ± 35.3 | 62.1 ± 37.8 | -0.5 ± 30.8 | 0.855 |
Mental | 47.0 ± 19.6 | 60.7 ± 15.6 | 13.7 ± 16.2 | 0.181 | 54.9 ± 27.7 | 50.0 ± 33.2 | -4.9 ± 23.3 | 0.854 |
Social | 54.2 ± 15.7 | 79.2 ± 3.6 | 25.0 ± 16.5 | 0.181 | 60.9 ± 33.2 | 65.6 ± 34.8 | 4.7 ± 22.5 | 1.000 |