Poster Session E - Tuesday Afternoon
Category: Biliary/Pancreas
Deepika Satish, MD
Memorial Sloan Kettering Cancer Center
New York, NY
Patient | Cancer Type | ICI | DM prior to ICI | Time to Onset of EPI (weeks) | Time to Onset of Hyperglycemia (weeks) | Clinical Presentation | Presenting Glucose (mmol/L) | Presenting A1c (%) | Presenting Fructosamine (mcmol/L) | C peptide | Auto-antibodies | Recent steroid use | DM agent | Type of Hyperglycemia |
55M | Melanoma | CTLA-4/PD-1 | No | 81 | 178 | DKA | 307 | 8.9 | NR | 0.1 | IA-2 | No | Insulin | Type 1 DM |
73F | Lymphoma | PD-1 | No | 86 | 76 | Asymptomatic | 129 | 6.5 | 288 | NR | NR | No | none | Unclear |
62M | Genitourinary | PD-1 | No | 78 | 74 | Asymptomatic | 172 | 6.4 | NR | NR | NR | No | PO | Type 2 DM |
59M | GI/HPB | PD-L1 | Yes | 70 | NA | NA | NA | NA | NA | 0.41 | NR | No | Insulin | Type 2 DM |
67M | Melanoma | CTLA-4/PD-1 | No | 15 | 11 | Acute Hyperglycemia | 404 | 9.3 | 346 | 2.94 | NR | Yes | PO | Type 2 DM |
61F | Melanoma | CTLA-4/PD-1 | No | 79 | 413 | Asymptomatic | NR | NR | NR | NR | NR | No | PO | Type 2 DM |
56F | Genitourinary | CTLA-4/PD-1 | No | 81 | 85 | Asymptomatic | 123 | 7.1 | 274 | 2.11 | NR | No | none | Type 2 DM |
50F | Lung | CTLA-4/PD-1 | Yes | 39 | NA | NA | NA | NA | NA | 3.06 | NR | No | Insulin + PO | Type 2 DM |
57M | Lung | PD-1 | No | 21 | 25 | Acute Hyperglycemia | 594 | 9.8 | NR | 1.19 | None | Yes | PO | Steroid Induced Hyperglycemia |
47M | Melanoma | CTLA-4/PD-1 | No | 2 | 11 | Acute Hyperglycemia | 470 | 8 | NR | < 0.2 | GAD | Yes | Insulin | Type 1 DM |
68M | Sarcoma | CTLA-4/PD-1 | No | 49 | 55 | Asymptomatic | 131 | 6.5 | NR | NR | NR | No | PO | Type 2 DM |