Caitlin E. Ross, Caitlin Ross, BS

Graduate Research Assistant
Department of Animal Science, University of Nebraska - Lincoln

I study the second isoform of gonadotropin releasing hormone (GnRH-II) and its cognate receptor (GnRHR-II), with our laboratory's specific focus geared toward understanding how this ubiquitous ligand-receptor complex affects physiological parameters associated with mammalian reproduction differently from the classical GnRH-I/GnRHR-I system. It is known that pigs are the only livestock species to encode a functional protein for both the ligand and receptor; therefore, we created a transgenic swine line with reduced endogenous levels of GnRHR-II (GnRHR-II KD) in order elucidate the role of GnRH-II and its receptor in porcine reproductive function. My strong background within the agricultural industry, specifically within the swine sector, as well as my previous academic and work experience have all influenced my performance as an animal researcher both inside and outside of our laboratory. We perform a large range of applied and molecular studies, including, but not limited to: computer-assisted semen analyses; extensive antemortem blood collections and serum hormone studies; postmortem tissue collections; and basic animal husbandry and welfare practices such as implementing proper vaccination schedules and feeding regimens. My research specifically focuses on how GnRH-II and its receptor impact spermatogenesis and/or sperm function within mature boars, as well as reproductive hormone secretory patterns of mature gilts during the estrous cycle, and how these potential findings could provide an avenue for future reproductive therapies.