P0278 - Bowel Preparation for Colonoscopy With Sodium Phosphate Solution versus Polyethylene Glycol-Based Lavage

Muhammad Adeel Farooq, MBBS¹, Asha Devi Oudha Ram, MBBS¹, Farina Hanif, MBBS, FCPS², Nasir Luck, MBBS, FCPS (Med), FCPS (Gastro)¹, Abbas Ali Tasneem, MBBS, FCPS (Med), FCPS (Gastro)¹, Zain Majid, MBBS, FCPS (Gastro)¹, Hina Ismail, MBBS^2
1Sindh institute of Urology and Transplantation, Karachi, Sindh, Pakistan; ²Sindh Institute of Urology and Transplantation, Karachi, Sindh, Pakistan

Introduction: Appropriate bowel preparation is cornerstone for detection of pathology during colonoscopy. The ideal preparation should not only ensure proper visualization of colonic mucosa but also should be tolerable and in-expensive. Both oral sodium phosphate containing and polyethylene glycol-based lavage are used predominantly as bowel cleansing modalities. Hence, we aim to assess the efficacy and tolerability of the two bowel preparation regimens for colonoscopy.

Methods: Patients were randomized into two groups, Group 1 ; polyethylene glycol (PEG) (236gm in two liter water in two divided doses) and Group 2 received sodium phosphate (NaP) (90ml in two divided doses). Endoscopist was blinded to the type of preparation. Efficacy was measured by using Boston Bowel Preparation Scale (BBPS) scale. BBPS score more than 6 was labelled as optimum preparation. Tolerability was assessed by symptoms; nausea, abdominal pain, vomiting and abnormal taste.

Results: In total 102 patients ; 58 (56.9%) were males . The mean age was 44.59 ± 13.9 years and mean weight was 57.63 ± 12.6 kg. NaP preparation was used in 53 (52%) while PEG based preparation in 49 (48%) patients, respectively. Median BBPs score was 7. Majority of study population (72.5%) had optimum preparation. In comparison to NaP preparation, patients with PEG based colo- prep had BBPS score of ≥ 6 (p= 0.02). Patient became nauseated (p = 0.05) and developed altered taste (p = < 0.001) with NaP preparation. While solution tolerability was better with PEG based preparation. (p= < 0.001)

Discussion: Colonoscopy preparation is more efficacious and well tolerable with polyethylene glycol-based lavage as compared to sodium phosphate containing solution.


Disclosures:
Muhammad Adeel Farooq indicated no relevant financial relationships.
Asha Devi Oudha Ram indicated no relevant financial relationships.
Farina Hanif indicated no relevant financial relationships.
Nasir Luck indicated no relevant financial relationships.
Abbas Ali Tasneem indicated no relevant financial relationships.
Zain Majid indicated no relevant financial relationships.
Hina Ismail indicated no relevant financial relationships.


Muhammad Adeel Farooq, MBBS¹, Asha Devi Oudha Ram, MBBS¹, Farina Hanif, MBBS, FCPS², Nasir Luck, MBBS, FCPS (Med), FCPS (Gastro)¹, Abbas Ali Tasneem, MBBS, FCPS (Med), FCPS (Gastro)¹, Zain Majid, MBBS, FCPS (Gastro)¹, Hina Ismail, MBBS². P0278 - Bowel Preparation for Colonoscopy With Sodium Phosphate Solution versus Polyethylene Glycol-Based Lavage, ACG 2021 Annual Scientific Meeting Abstracts. Las Vegas, Nevada: American College of Gastroenterology.