P2551 - Hospitalizations With Upper and Lower GI Bleeding Following Admission for Venous Thromboembolism

Viraj Shah, MD¹, Dhruvil Radadiya, MD², Kalpit Devani, MD^3
1Florida Atlantic University, Boca Raton, FL; ²University of Kansas Medical Center, Kansas city, KS; ³University of South Carolina, Greenville, SC

Introduction: Initiation of Anticoagulation following Venous Thromboembolism (VTE) is a standard practice. Thus, such patients following VTE, are at higher risk of gastrointestinal bleeding. Data regarding hospital admission with GI bleeding (GIB) following the VTE event remains unavailable. Here, we looked at how many patients were getting admitted with GI bleeding at day 30, 60 and 90.

Methods: We used the national readmission database for year 2017. Adult patients with VTE (PE and DVT of extremities) were identified using ICD 10 codes. Patients with a concurrent discharge diagnosis of GIB were identified using a previously validated algorithm and excluded from the study. Patients remaining thereafter were tracked for readmissions with GIB at day 30, 60 and 90 using the unique ID number for each admission. We further subclassified patients into upper and lower GIB (UGIB and LGIB) class to see if there was a difference amongst both over time. All the readmissions were reported as percentage of total number of patients.

Results: We identified 637,625 patients with VTE from database, out of which 18,105 (2.8%) patients were excluded as concurrent GI bleeding was present in the same admission. Males and females were equally distributed. Mean age of patients were 63.8 years. As shown in figure 1, 30-day readmission rate for GIB regardless of the source was 0.98%, for upper GIB it was 0.7%, while for lower GIB it was 1.5%; 60-day readmission rate for GIB regardless of the source was 1.26%, for upper GIB it was 0.93%, while for lower GIB it was 0.78%. The 90-day readmission rate for GIB regardless of the source of bleeding was 1.43%, for upper GI bleeding it was 1.04% and for lower GI bleeding it was 0.89%.

Discussion: The percentage of hospitalizations with GIB following initial admission with VTE progressively increased over time. Risk of readmission with lower GI bleeding was highest at day 30, whereas risk of readmission with upper GI bleeding was highest at day 90.



Disclosures:


Viraj Shah, MD¹, Dhruvil Radadiya, MD², Kalpit Devani, MD³. P2551 - Hospitalizations With Upper and Lower GI Bleeding Following Admission for Venous Thromboembolism, ACG 2021 Annual Scientific Meeting Abstracts. Las Vegas, Nevada: American College of Gastroenterology.