John H. Stroger, Jr. Hospital of Cook County Chicago, IL, United States
Syed Ali Amir Sherazi, MD1, Hemant Goyal, MD, PGDCA (MBA)2, Ikechukwu Achebe, MD1, Jennifer Asotibe, MD1, Attar Bashar, MD1 1John H. Stroger, Jr. Hospital of Cook County, Chicago, IL; 2Wright Center for Graduate Medical Education, Scranton, PA
Introduction: Microscopic colitis (MC) is a chronic inflammatory bowel disease diagnosed histologically with a macroscopically normal large bowel. It is 2.4 times more common in women with over 75% patients >50 years old (Gastroenterol Hepatol 2017;13(11):671-5). Most MC studies are small with scarce data about its effects on healthcare utilization. The aim of our study was to evaluate gender-based differences in demographics, outcomes and healthcare utilization in MC from a national database
Methods: The US Healthcare Cost and Utilization Project’s National Inpatient Sample (HCUP-NIS) 2016-2018 was queried to identify patients with MC using ICD-10 codes. We studied men and women for differences in patient and hospital demographics, comorbidities, complications, mean length of stay (LOS), mean Total Hospital Charges (THC), adjusted all-cause mortality. Statistical analysis utilized chi-square test, univariate and multinomial logistic regression
Results: A total 7,145 MC admissions were identified with 1,965 men and 5,180 women (M:F ratio of 1:2.6). Overall, 90.5% were >50 years old (91.5% women and 88% men). Compared to men, women were non-significantly older (mean age 71.2 vs 69,2, p=0.054), white (90.8% vs 86.7%, p=0.2), less Hispanic (3.7% vs 7.2%, p=0.2). Treating Hospital size, teaching status, region, income quartile zip codes where patients hailed from and insurance types were similar between groups. Men had significantly higher rates of diabetes, coronary artery disease, heart failure, chronic kidney disease and smoking (all p< 0.001) while women had higher rates of hypertension (p=0.002). Dyslipidemia, obesity, COPD were similar between groups. Celiac disease and rheumatoid arthritis prevalence (known to increase risk of MC) was also similar. LOS was higher for men (5.3 vs 4.8 days, p=0.023), non-significant when adjusted for patient and hospital demographics. THC were similar between the groups ($51,642 men vs $48,103 women, p=0.14). There were 60 total deaths (0.8%) with no difference between the groups
Discussion: MC is more common with age with much higher proportion ( >90%) of patients >50 years old than previously reported. Women had higher prevalence (M:F ratio 1:2.6). Women with MC were more likely to be white and less likely Hispanic. While men had significantly higher rates of medical co-morbidities than women, it did not translate into higher healthcare utilization, indicating the need to explore why women with MC are utilizing healthcare as much as men despite less medical problems
Disclosures: Syed Ali Amir Sherazi indicated no relevant financial relationships. Hemant Goyal indicated no relevant financial relationships. Ikechukwu Achebe indicated no relevant financial relationships. Jennifer Asotibe indicated no relevant financial relationships. Attar Bashar indicated no relevant financial relationships.
Syed Ali Amir Sherazi, MD1, Hemant Goyal, MD, PGDCA (MBA)2, Ikechukwu Achebe, MD1, Jennifer Asotibe, MD1, Attar Bashar, MD1. P1197 - Gender-Based Differences in Microscopic Colitis: Analysis of Demographics, Outcomes and Healthcare Utilization From a National Database, ACG 2021 Annual Scientific Meeting Abstracts. Las Vegas, Nevada: American College of Gastroenterology.
