P2607 - Race Stratified Trends in Hospitalizations for Inflammatory Bowel Disease Flare: A Retrospective Cohort Study

Tuesday, October 26, 2021

10:30 AM – 4:00 PM PT

Location: Shoreline Exhibit Hall

Has Audio

Presenting Author(s)

IA

Ikechukwu Achebe, MD

John H. Stroger, Jr. Hospital of Cook County
Chicago, IL, United States

Ikechukwu Achebe, MD¹, Chimezie Mbachi, MD², Jill Gaidos, MD, FACG²
¹John H. Stroger, Jr. Hospital of Cook County, Chicago, IL; ²Yale University School of Medicine, New Haven, CT

Introduction: Inflammatory bowel disease (IBD) describes a state of chronic, intermittent gastrointestinal inflammation, and remains a significant cause of inpatient morbidity. This study provides data on the nationwide trend of hospitalizations for IBD in the United States, after stratification by race. Given the significance that socioeconomic factors play on access to health care, we aim to examine the influence of household income on trends of hospitalizations for IBD in each of the major ethnic groups.

Methods: The Healthcare Cost and Utilization Project’s (HCUP) National Inpatient Sample (NIS) was sourced for data involving adult hospitalizations for patients admitted with IBD (2005 to 2014). ICD-9 codes were used to query patients, and analysis of trend data was conducted using the Cochran-Mantel-Haenszel χ2 test of linear association. P values < 0.05 were considered statistically significant. The main outcome was percent change in number of admissions over the study period, stratified by race. Our secondary outcome analyzed race stratified trends in the percent of patients belonging to the four quartiles of family income. Analysis was done using SPSS software.

Results: 232,910 adults were admitted from 2005 to 2014 with a primary diagnosis of IBD; UC (N= 81,232; 34.9%) CD (N= 151,678; 65.1%). Over the study period, Caucasian (CAU) patients with IBD were the single cohort with a decreasing trend in the number of admissions, and a decrease in percent change from 2005 to 2014 (%Δ = -7.55%). All other races had increasing trends in admissions and an increase in percent change of admissions. African American’s (AA: %Δ = +32.3%), Hispanic’s (HSP: % Δ = +29.3), Asians Native American, and others (%Δ = +27.8). Linear by linear association was significant (p ≤ 0.001) for all aforementioned trends (Fig, Tab, 1). By the study's end, AA patients had the greatest proportion of their cohort belonging to the poorest quartile of household income (Q1; AA: 47.2%, HSP: 35.70% CAU: 20.9%), and entered this quartile at the quickest rate (Fig 2).

Discussion: Healthcare disparity remains a complicated and costly burden. Research has shown the patients belonging to lower socioeconomic classes have limited access to healthcare, reduced health literacy, and environmental realities that contribute to increased morbidity and mortality. Our findings of increasing IBD-related hospitalizations and a greater percentage of minority patients in the poorest quartile highlight the impact of socioeconomic determinants.

Figure: Figure 1 (a, b): Display of the trend in IBD-related admissions stratified by race as proportions of the total number of IBD patients admitted (2005-2014). Linear by linear association was significant (p ≤ 0.001) for all aforementioned trends. Figure 2 (a, b, c): Display of the yearly trend in patients belonging to one of the four quartiles of family income. (Q1) $1 - $45,999, (Q2) $46,000 - $58,999, (Q3) $59,000 - 78,999, (Q4) $79,000+

Table 1: Temporal Trend in IBD Related Admissions Stratified by Race
Year	Caucasian	African American	Hispanic	Asian, Native Amer, Other
2005	80.8%	9.90%	5.8%	3.6%
2006	78.1%	10.9%	7.2%	3.9%
2007	76.5%	11.5%	7.6%	4.4%
2008	76.9%	10.0%	8.2%	4.8%
2009	78.4%	10.6%	6.5%	4.6%
2010	75.6%	12.9%	6.8%	4.8%
2011	75.1%	13.9%	6.9%	4.1%
2012	75.4%	13.0%	6.9%	4.8%
2013	75.2%	12.7%	7.6%	4.4%
2014	74.7%	13.1%	7.5%	4.6%
Rate of change	-0.0054x	+0.0038x	+0.0007x	+0.0008x
Percent Change (%Δ)	-7.55%	+32.3%	+29.3	+27.8

Table: Table 1: Temporal trends in IBD-related admissions stratified by race proportions. Linear by linear association was significant (p ≤ 0.001) between groups.

Disclosures:

Ikechukwu Achebe indicated no relevant financial relationships.

Chimezie Mbachi indicated no relevant financial relationships.

Jill Gaidos indicated no relevant financial relationships.

Ikechukwu Achebe, MD¹, Chimezie Mbachi, MD², Jill Gaidos, MD, FACG². P2607 - Race Stratified Trends in Hospitalizations for Inflammatory Bowel Disease Flare: A Retrospective Cohort Study, ACG 2021 Annual Scientific Meeting Abstracts. Las Vegas, Nevada: American College of Gastroenterology.