Category: HAI: Disinfection/Sterilization & Environmental Infection Prevention

Poster Session: HAI: Disinfection/Sterilization & Environmental Infection Prevention

820 - Impact of pulsed xenon ultraviolet (PX-UV) light disinfection for reduction of pathogens on high touch surfaces following hospitalization

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Presenting Author(s)

Joud N. Jarrah

Infectious Diseases Fellow
Wayne State University / Detroit Medical Center
Detroit, Michigan
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Co-Author(s)

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Oscar I. Martinez

Physician
Wayne State University
Sterling Heights, Michigan
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
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Susmita jain

Research coordinator
Detroit Medical Center
Detroit, Michigan
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Piyali Chatterjee

Senior Research Scientist
Central Texas Veterans Health Care System
Temple, Texas
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Hosoon Choi

Senior Research Scientist
Central Texas Veterans Health Care System
Temple, Texas
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Munok Hwang

Research Technician
Central Texas Veterans Health Care System
Temple, Texas
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
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Morgan Bennett

Research coordinator
Central Texas Veterans Health Care System
Temple, Texas
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
JulieAnn Martel

Research Assistant
Central Texas Veterans Health Care System
Temple, Texas
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
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Jing Xi

Research Technician
Central Texas Veterans Health Care System
Temple, Texas
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
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Mark Stibich

Co-Founder of Xenex Germ-Zapping Robots
Xenex Germ-Zapping Robots
San Antonio, Texas
Disclosure: Xenex Germ-Zapping Robots (Board Member, Grant/Research Support)
Keith S. Kaye

Professor of Medicine
Rutgers Robert Wood Johnson Medical School
New Brunswick, NJ
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Chetan Jinadatha

Chief, Infectious Diseases Section
Central Texas Veterans Health Care System
Temple, Texas
Disclosure: AHRQ (Research Grant or Support)Department of Veterans Affairs (Other Financial or Material Support, Owner: Department of Veterans Affairs. Licensed to: Xenex Disinfection System, San Antonio, TX)Inventor (Other Financial or Material Support, Methods for organizing the disinfection of one or more items contaminated with biological agents)NiH/NINR (Research Grant or Support)NSF (Research Grant or Support)Xenex Healthcare Services (Research Grant or Support)
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Sorabh Dhar

MD
John D Dingell VA medical Center
Detroit, Michigan
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.

Background: Ultraviolet (UV) light disinfection following a manual terminal cleaning process for hospital rooms has been proposed as an additional method to reduce the bacterial burden on surfaces. The impact of UV light disinfection and the level of interdependence between the modalities remains unclear.

Methods: Samples were collected from 5 high touch surfaces from 10 patients room following discharge prior to manual disinfection, following manual disinfection, and following pulsed xenon UV disinfection using Rodac contact plates (total 150 samples). Colonies were identified using MALDI-TOF mass spectrometry. The bacterial colony counts were recorded and analyzed as pathogenic or commensal organisms (based on CDC criteria) to assess the efficacy of the disinfection process.

Results: Average colony counts for the rooms prior to disinfection, post disinfection, and post UV light were 185.8 CFU +/- SD 280, 43 CFU +/- 121, and 20 CFU +/- 36.7 respectively. The average drop in colony-forming units of the five high touch areas in patient's rooms can be seen in table 1. Twelve commensal bacterial species were isolated: Bacillus species (sp.), Corynebacterium sp., Enhydrobacter sp., Kocuria sp., Lysinibacillus sp., Macrococcus sp., Micrococcus sp., Paenibacillus sp., Pantoea sp., Psychrobacter sp., Siccibacter sp., Coagulase negative staphylococcus . Seven pathogenic bacteria were isolated: Acinetobacter sp., Brucella sp., Proteus sp., Staphylococcus aureus, Escherichia sp., Enterococcus, and Pseudomonas aeruginosa. Reductions in the predominant bacterial species following disinfection modality are noted in table 2.Table 1: Colony forming units (CFUs) average Pre-disinfection (Pre-Dis), Post Disinfection (Post-Dis), and Post PX-UV Light (PX-UV).

Table 2: Sub-analysis of commensal and pathogen isolation Pre-Disinfection (Pre-Dis), Post-Disinfection (Post-Dis), and Post PX-UV light ( PX-UV).

Conclusion: A combination of manual disinfection and UV has shown a notable additional reduction in overall bacterial contamination of the patient rooms, including the majority of high touch areas as compared with manual disinfection alone. No additional reduction in commensal bacteria isolates was noted after UV light, however a further decrease in pathogenic bacteria (Acinetobacter and Enterococcus) was noted. UV light may be considered as an additional room disinfection method to reduce overall bacterial burden and pathogenic bacterial contamination of rooms as a comprehensive strategy to reduce nosocomial infections.