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Category: Respiratory Infections - Viral
Poster Session: Respiratory Infections - Viral
Mina Suh
Senior Epidemiologist
Epidstrategies
Mission Viejo, California
Disclosure: EpidStrategies (Employee)
Xiaohui Jiang
Senior Statistician
EpidStrategies, A Division of ToxStrategies, Inc.
Rockville, MD
Disclosure: EpidStrategies (Employee)
Naimisha Movva
Epidemiologist II
Epidstrategies
Rockville, Maryland
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Joh Frysek
Principal Epidemiologist/Practive Director
Epidstrategies
Rockville, Maryland
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Lauren Bylsma
Epidemiologist
Epidstrategies
Ann Arbor, Michigan
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Christopher Rizzo
Senior Medical Director
Sanofi
Swiftwater, Pennsylvania
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Christopher B. Nelson
Associate Vice President
Sanofi
Swiftwater, Pennsylvania
Disclosure: I do not have any relevant financial / non-financial relationships with any proprietary interests.
Respiratory syncytial virus (RSV) is a common cause of illness and hospitalization for infants and children globally. The objective of this study was to characterize the burden of RSV and all-cause bronchiolitis (ACB) inpatient hospitalizations and emergency room department (ED) visits in U.S. infants aged < 1 year with the most recent years of data available. |
The National (Nationwide) Inpatient Sample (NIS) and the Nationwide Emergency Department Sample (NEDS), which are large national publicly available all-payer databases in the U.S., were used to estimate the burden of RSV in 2016 based on ICD-9 and 10 codes. The proportions of hospitalizations or ED visits due to RSV in infants aged < 1 year were quantified. Due to the potential of missing RSV encounters based on coding practices, ACB was also evaluated. Based on availability of variables and data recency, 2011 NIS data were used to describe RSV burden by age in months. Sensitivity analyses were conducted with NIS and NEDS data from other years (2011-2015). |
These results show that during the RSV season, RSV and ACB were a leading cause of hospitalization and ED visit among US infants under 1 year of age. Current policy does not support routine RSV testing of clinical lower respiratory tract infections (LRTIs) among infants. In that context, as an approximation of RSV LRTI visits in each setting, ACB can be considered an upper bound and RSV can be considered a lower bound of the true proportion of hospital encounters associated with RSV in these settings.. |