Presentation Type: Virtual Poster

Program: Section on Minority Health, Equity, and Inclusion Program (H3805)

P0673 - Differences in food allergens and atopy between black and white children with food allergy in the FORWARD study

Background:
Racial differences in food allergy outcomes exist.

Objectives:
Our aim is to characterize phenotypic differences between black and white children with food allergy (FA).

Methods:
We are conducting a prospective multi-center cohort study enrolling African-American (AA) or Caucasian (W) children aged 0-12 years diagnosed with food allergy and seen in allergy/immunology clinics at four urban tertiary centers in the US. To test for associations between demographic variables (race, age) and allergy/atopy, we used chi-square tests for independence.

Results:
Currently there are 492 children (170 AA and 322 W) with complete intake information enrolled in the study. We found a significant association between race and self-reported allergies of fin-fish (AA 21.2%, W 8.1%, P<0.001), shellfish (AA 30%, W 7.5%, P<0.001), soy (AA 11.2%, W 5.6%, P<0.05), wheat (AA 13.5%, W 4.0%, P<0.01) and sesame (AA 8.2%, W 21.7%, P<0.001). In regards to comorbidities, AAs had a higher prevalence of allergic rhinitis (AR) and asthma than whites [40.9% W, 59.9% AA (P<0.001) and 58.9% AA, 27.8% W (P<0.001) respectively]. In relation to age, both races reported older children having a higher likelihood of AR and asthma (P<0.001) than younger children.

Conclusions:
We observed that AA children had higher odds of allergy to shellfish, fin-fish, soy and wheat while Whites had higher odds of allergy to sesame seed. We also found a significant association between race and AR/asthma, as well as race and age.

Co-Author(s)

AA

Aame B. Andy-Nweye

Research Coordinator
Rush University Medical Center
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed
SF

Susan Fox

Physician Assistant
Rush University Medical Center
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed
MM

Mahboobeh Mahdavinia

Assistant Professor
Rush University Medical Center
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed
MT

Mary C. Tobin

Associate Professor
Rush University Medical Center
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed
AC

Annika Chura

Clinical Research Coordinator
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio
Disclosure: No Financial Relationships Disclosed
AA

Amal Assa’ad

Professor
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio
Disclosure: No Financial Relationships Disclosed
AC

Amaziah Coleman

Allergist-Immunologist
Children’s National Medical Center
Washington, District of Columbia
Disclosure: No Financial Relationships Disclosed
AR

Adam Robinson

Clinical Research Coordinator
Children’s National Medical Center
Washington, District of Columbia
Disclosure: No Financial Relationships Disclosed
Hemant Sharma

Associate Professor
Children’s National Medical Center
Washington, District of Columbia
Disclosure: No Financial Relationships Disclosed
LB

Lucy Bilaver

Assistant Professor
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed
DB

Dannielle Brown

Research Fellow
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed
AB

Alexandria Bozen

Research Assistant
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed
JF

Jamie Fierstein

Senior Data Analyst
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed
IG

Isabel Galic

Research Assistant
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed

Presenting Author(s)

JJ

Jialing Jiang

Research Coordinator
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed

Co-Author(s)

Olivia R. Negris

Medical Student, Research Assistant
Northwestern University Feinberg School of Medicine
Wheaton, Illinois
Disclosure: No Financial Relationships Disclosed
PN

Pamela Newmark

Research Coordinator
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed
JP

Jacqueline Pongracic

Professor
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Disclosure: No Financial Relationships Disclosed
CW

Christopher Warren

Post-Doctoral Scholar
Stanford University
Stanford, California
Disclosure: No Financial Relationships Disclosed

Senior Author(s)

Ruchi S. Gupta

Professor
Northwestern University Feinberg School of Medicine
Chicago, Illinois
Disclosure: Aimmune Therapeutics (Consultant)BeforeBrands Inc (Consultant)DBV Technologies (Consultant)DOTS Technology (Consultant)Food Allergy Research & Education (Consultant)Food Allergy Research & Education (FARE) (Grant/Research Support)Genentech (Grant/Research Support)Genentech (Consultant)Kaleo Inc. (Consultant)National Confectioners Association (Grant/Research Support)National Institutes of Health (Grant/Research Support)Stanford Sean N. Parker Center for Allergy & Asthma Research (Grant/Research Support)ThermoFisher Scientific (Grant/Research Support)UnitedHealth Group (Grant/Research Support)YoBee Inc (Stockholder/Ownership Interest (excluding diversified mutual funds))